Ageing Clinical Trial
Official title:
The Acute Effect of Two Berry Extracts on Cognition and Mood in Adults Aged 40 to 60
The first study of my PhD showed that acute supplementation of berry extracts can modulate
cognitive behaviour in healthy adults. There is a growing body of evidence supporting an
improvement in memory and learning performance in animal models following the ingestion of
flavonoid rich fruits (Shukitt-Hale et al 2008;Spencer 2008; Spencer et al., 2008). However,
study 2, showed no effect on any aspects of memory in healthy young adults after
supplementation of the berry extracts. It is hypothesised that the lack of behavioural
effects on memory of the berry juice in study 2 was because of the cohort used. These
healthy adult participants were already performing near to their peak (Salthouse et al.,
2009), and unlike study one, participants were not mentally fatigued enough to reveal subtle
cognitive benefits.
The aims of the study are to examine if acute supplementation of two berry extracts in an
older population can augment memory, attention and executive function. Secondly, the time
course of these behavioural effects will be measured by multiple cognitive assessments
throughout the day after consumption of the extracts.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science
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