Age Determination by Skeleton Clinical Trial
— SAASOfficial title:
Swedish Age Assessment Study -SAAS Study to Deepen the Knowledge of Magnetic Camera Examinations as a Method for Medical Age Assessment
Verified date | June 2018 |
Source | Karolinska Institutet |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
It is important that asylum seekers should have as accurate age assessment as possible and
that children's fundamental rights are met by choosing methods based on best available
knowledge. The aim is to provide, on the basis of best available knowledge, suggestions for
methods of medical age assessment of whether a person is over or under 18 years of age.
The primary issue is to investigate whether five selected growth zones in knee joint, ankle
and wrist individually or in combination can better determine the 18-year limit compared with
previous research.
Status | Completed |
Enrollment | 958 |
Est. completion date | April 30, 2018 |
Est. primary completion date | April 30, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 14 Years to 21 Years |
Eligibility |
Inclusion Criteria: - Healthy children / young adults without prior illness (such as asthma, growth hormone treatment, prolonged peroral cortisone treatment, cancer treatment, diabetes, rheumatic disease) that may have affected growth can be included in the study. Exclusion Criteria: - Children or adolescents with ongoing drug treatment for chronic disease. - Contraindication against MRI examination - Pregnancy |
Country | Name | City | State |
---|---|---|---|
Sweden | Blekinge Institute of Technology | Karlskrona | |
Sweden | Karolinska Institute | Stockholm |
Lead Sponsor | Collaborator |
---|---|
Berit Larsson | Blekinge Institute of Technology, Karolinska Institutet, Ministry of Health and Social Affairs, Sweden |
Sweden,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of participants with correctly classified age (below or above 18 years) when 5 different growth zones in the knee, ankle and wrist are examined by MRI and analysed individually and in combination to determine the maturity. | With 1.5 Tesla magnetic camera with dedicated cartilage sequence, selected growth zones will be investigated: knee joint, ankle joint including heel leg and wrist. The non-dominant body half will be investigated. In order to evaluate the growth zone with the highest precision, we have chosen T2-weighted gradient-recalled echo sequence, called mFFE / MERGEĀ® / MEDICĀ® by various suppliers. The sequence is used in the clinical practice to assess various types of abnormalities in the cartilage. Two independent and blinded child radiologists shall examine MR images of 5 growth zones of each participant. All sections of each growth zone are to be examined and the cut is selected which shows the highest degree of closing / maturity for grading. Each growth zone will be examined and classified as being mature or non-mature. | 1 day |