Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine if an electronic alerting technology improves time to intervention for possible ADEs, identify what factors affect adoption of ADE alerts, and whether there is a cost benefit associated with the alerting technology.


Clinical Trial Description

Inpatient adverse drug events (ADEs) continue to be a major source of morbidity and mortality despite advances in computerized drug safety measures. Reports on the ability of computerized ADE alerts to prevent and mitigate ADEs are lacking. The aims of this project are to 1) Assess organizational, social, and cognitive factors that affect adoption of real-time ADE alerting technology; 2) Analyze the effect of the ADE alerting technology on management and rate of ADEs; and 3) Estimate the cost-benefit of the ADE alerting technology. This study will use a patient randomized design of computerized real-time ADE alerts intended for primary and secondary prevention of ADEs. The ADE alerts promise to reduce mortality, morbidity, and costs due to ADEs. This study will quantify the effect of the alerts in the hands of first-year medical residents and pharmacists. The study will explore the associations of organizational and soci-cognitive barriers and facilitators with the adoption of the ADE alert technology. At the cognitive level, it will explore whether ADE Alerts change user bias in diagnosing ADEs or whether the alerts heighten sensitivity to drug problems. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research


Related Conditions & MeSH terms


NCT number NCT00780572
Study type Interventional
Source VA Office of Research and Development
Contact
Status Completed
Phase N/A
Start date December 2008
Completion date March 2011

See also
  Status Clinical Trial Phase
Completed NCT02239237 - Post-marketing Safety Surveillance of Compound Kuh-seng Injection: a Registry Study
Completed NCT01179867 - Using Novel Canadian Resources to Improve Medication Reconciliation at Discharge N/A
Completed NCT02191358 - YouScript IMPACT Registry N/A
Completed NCT02059044 - Information Systems-enabled Outreach Program for Adverse Drug Events N/A
Completed NCT01164137 - Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care N/A
Completed NCT02482025 - The Secure Messaging for Medication Reconciliation Tool (SMMRT) Trial N/A
Completed NCT04692220 - Drug-Related Problems : Focus on Age and Diabetes
Completed NCT02378220 - Pharmacogenetic Testing Among Home Health Patients N/A
Completed NCT01337063 - Multi-Center Medication Reconciliation Quality Improvement Study N/A
Completed NCT02593916 - Response to Medication Registry
Completed NCT00013143 - Patient Profiling and Provider Feedback to Reduce Adverse Drug Events N/A
Withdrawn NCT00606606 - Reducing Adverse Drug Events in the Nursing Home N/A
Completed NCT02805270 - Impact of Medication Reconciliation Intervention on the Rate of Preventable Adverse Drug Events (ADEs) and Healthcare Utilization N/A
Completed NCT02026453 - Pharmacists and Pharmacy Technicians to Improve Admission Medication History Accuracy N/A
Completed NCT01764204 - Hospital Intensive Monitoring of Adverse Drug Reactions of Qingkailing Injection In The Next Two Years N/A
Completed NCT01531088 - Enhancing the Detection and Management of Adverse Drug Events in Nursing Homes N/A
Completed NCT02122965 - The Effect of Medication Review in High-risk Emergency Department Patients N/A
Completed NCT01091038 - Improving Safety by Basic Computerizing Outpatient Prescribing Phase 2/Phase 3
Recruiting NCT04479553 - Post-marketing Safety Surveillance of Qizhi Tongluo Capsules:a Registry Study.
Active, not recruiting NCT00740675 - Ambulatory Medication Reconciliation Following Hospital Discharge N/A