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Clinical Trial Summary

In this study, a new post-processing image technology - radiomics is used to screen out parameters of CT and MRI images, which could effectively evaluate the efficacy and prognosis of immunotherapy plus targeted therapy for soft tissue sarcoma (STS). A reliable and effective model for predicting the prognosis of STS will be established based on the radiomic parameters combined with traditional imaging, histophiological, whole exome sequencing (WES) results, inflammatory indicators and changes in the number and function of lymphocyte subsets before and after medication. Patients with advanced STS who may benefit from the combination therapy can be found out by this model.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06062927
Study type Observational
Source Peking Union Medical College Hospital
Contact Xiang Wang
Phone 69158754
Email wangxiang5123@126.com
Status Recruiting
Phase
Start date February 2, 2023
Completion date February 2, 2027

See also
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Completed NCT01684449 - Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma Phase 1/Phase 2
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Active, not recruiting NCT03660930 - Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas Phase 1/Phase 2