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Ningetinib in Advanced NSCLC Skipping Mutations With MET Exon 14 Skipping Mutations

Advanced NSCLC Clinical Trial

Official title:
A Phase II Study of the Ningetinib in Advanced NSCLC With MET Exon 14 Skipping Mutations

Clinical Trial Summary

This is a phase II, Single-arm,Open-label Study evaluating the safety and efficacy of CT053PTSA in Advanced Solid Tumors With MET Exon 14 Skipping Mutations

Clinical Trial Description

This study is being carried out in two parts, part 1 and part 2. Part 1:Observation phase of dose tolerance: Objective To observe the tolerability and safety of 60 mg CT053PTSA in advanced NSCLC patients with Metex14 skipping mutation, and to determine the recommended dose (RED) in the dose expansion phase。 Part 2: This is the expansion part and will continue to evaluate the safety and efficacy of CT053PTSA at the dose of RED in advanced NSCLC patients with Metex14 skipping mutation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04992858
Study type Interventional
Source Sunshine Lake Pharma Co., Ltd.
Contact Li Zhang, MD
Phone (086)020-87343458
Email zhangli@sysucc.org.cn
Status Not yet recruiting
Phase Phase 2
Start date November 27, 2022
Completion date December 9, 2024
View Details
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