Advanced Breast Cancer Clinical Trial
Official title:
A Phase Ib Study to Evaluate the Tolerability and Pharmacokinetics of Selatinib Ditosilate Tablets in Patients With Advanced Breast Cancer
Brief Description:
This study is designed to evaluate the safety and tolerability of oral Selatinib Ditosilate
Tablets, and explore the maximum tolerated dose (MTD) and dose-limiting toxicity in patients
with advanced breast cancer.
1. To evaluate the safety and tolerability of oral Selatinib Ditosilate Tablets, and
explore the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT).
2. To determine the pharmacokinetic profile of single and multi oral Selatinib Ditosilate
Tablets .
3. To determine preliminary dose and regimen for phase II study of oral Selatinib
Ditosilate Tablets.
4. To assess preliminary antitumor activity .
;
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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