Adult Glioblastoma Clinical Trial
Official title:
18F FDOPA PET/CT or PET/MRI in Patients With Gliomas
This clinical trial compares fluorine F 18 fluorodopa (18F FDOPA) positron emission tomography (PET) with standard magnetic resonance imaging (MRI) in measuring tumors in patients with glioma that is newly diagnosed or recurrent (has returned). 18F FDOPA is a radioactive drug that binds to tumor cells and is captured in images by PET. Computed tomography (CT) and MRI are used with PET to describe information regarding the function, location, and size of the tumor. PET/CT or PET/MRI may be more accurate than standard MRI in helping doctors find and measure brain tumors.
PRIMARY OBJECTIVES:
I. To evaluate 18F-FDOPA PET obtained from PET/CT or PET/MRI imaging in patients with newly
diagnosed or recurrent gliomas.
OUTLINE:
Patients receive 18F FDOPA intravenously (IV) and then undergo PET/CT or PET/MRI 10-30
minutes later.
After completion of study, patients are followed up at 24 hours and at 1 week.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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