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NCT05328570 Clinical Trial

Comparing the Effects of Exercise on the Structure and Function of Fat Tissue

Adiposity Clinical Trial

— CAT  

Official title:
Effects of Exercise Training on the Structure and Metabolic Function of Fat Tissue

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT05328570
Other study ID # HUM00179332
Secondary ID
Status Enrolling by invitation
Phase N/A
First received
Last updated
Start date June 4, 2020
Est. completion date September 2025

Study information
Verified date June 2024
Source University of Michigan
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Assess differences in structure and biological function of abdominal subcutaneous adipose tissue samples collected from adults who exercise regularly vs. a well-matched cohort of non-exercisers.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 50
Est. completion date September 2025
Est. primary completion date September 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria: - Age: 18-40 years old - Body Mass Index: 23-35 kg/m2 - Women must have regularly occurring menses and must be premenopausal Exclusion Criteria: - Evidence/history of cardiovascular or metabolic disease - Medications known to affect lipid or glucose metabolism, or inflammation - Weight instability = ± 6 pounds in the last 6 months - Tobacco or e-cigarette users - Women must not be pregnant or actively lactating - Blood pressure > 140/90 mmHg

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Oral Glucose Tolerance Test
Subjects will complete an Oral Glucose Tolerance Test in which glucose is given and blood samples are taken every 15 minutes over a 2 hour period to determine how quickly the glucose is cleared from the blood.

Locations
Country Name City State
United States University of Michigan Ann Arbor Michigan

Sponsors (1)
Lead Sponsor Collaborator
University of Michigan

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Blood Glucose Level mg/dL 2 hours at Experimental Trial
Primary Adipose tissue fibrosis Pico-sirius Red stain (percent stained) baseline
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