A Randomized Control Study of Anti-Adhesion Agent After Colorectal Surgery

Status Recruiting

Clinical Trial Summary

This project is to evaluate the difference of post-operation adhesion severity and adhesion area of patient received 4DryField after colorectal surgery.

Clinical Trial Description

This proposal will investigate the effect of the newly anti-adhesive agent 4DryField. Stoma creation is common in complicated colorectal disease. Hartman procedure (End colostomy) is used in patients advanced rectal cancer or severe diverticulitis. Loop colostomy or ileostomy is used in patients need stool diversion for prevent leakage related infection. 4DryField is a powder consisting of sterile hydrophilic microparticles, which is anufactured from highly purified potato starch in a complex process. A unique starch-based medical device is 4DryField® PH (4DryField; PlantTec Medical GmbH, Germany) as it is the only product proven to provide hemostasis and prevent the formation of adhesions. In rat model, the 4DryField acheieve the significant adhesion prevention effectiveness. In gynecologic surgery, 4DryField showed effective adhesion prevention as confirmed at second look laparoscopy. The gel is easilier to applied in the uneven surface of pelvic cavity and peristomy area than other manufacture. The indication of adhesion prevention is approved by TFDA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05580471
Study type	Interventional
Source	Taipei Medical University Shuang Ho Hospital
Contact	Tungcheng Chang, PhD
Phone	+886-2-22490088
Email	rotring810@yahoo.com.tw
Status	Recruiting
Phase	N/A
Start date	March 5, 2022
Completion date	September 4, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05265559` - Influence of Operator Factors on Succes and Survival of Indirect Restorations
Not yet recruiting	`NCT04641923` - The Efficacy of a Topical Anti-adhesive Film for Decreasing Perihepatic Adhesions in Repeat Hepatic Surgery	N/A
Completed	`NCT03443583` - Immediate and Delayed Dentin Sealing Effect on Partial Crowns	N/A
Completed	`NCT03660787` - Efficacy and Dose Ranging Study of Seroguard	Phase 2
Completed	`NCT03640559` - Safety and Tolerability of Seroguard Use	Phase 1
Active, not recruiting	`NCT04271150` - Efficiency of Different Modes of Universal Adhesive	N/A
Active, not recruiting	`NCT02434601` - Dentin Treatments for Restorations of Cervical Lesions Non-Carious	Phase 2/Phase 3
Recruiting	`NCT05811585` - PMCF Study for ADEPT® in LaparoscopicGynecologic Surgery
Completed	`NCT05036525` - Evaluation of the Efficacy and Safety of a Hyaluronic Acid Gel in Adhesion Prevention After Open Thyroidectomy.	N/A
Not yet recruiting	`NCT04475367` - Evaluation of the Effect of an APP in Improving Treatment Adherence in Hypertensive Patients in Hypertension Ambulatory	N/A
Completed	`NCT03293186` - Anti-adhesive Effect and Safety of "Thermo-sensitive Adhesion Barrier (MEDICLORE)"	Phase 4
Completed	`NCT04023383` - New Cross Linked Hyaluronan Gel After Deep Infiltrating Endometriosis Surgery	N/A
Completed	`NCT04837469` - Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month	N/A
Active, not recruiting	`NCT05996809` - PMCF Study for COSEAL® in Gynecologic Surgery
Completed	`NCT05999162` - Mechanical Ileus in the Era of Minimally Invasive Colorectal Surgery
Not yet recruiting	`NCT05415059` - LEAFix Adhesion in Healthy Volunteers	N/A
Active, not recruiting	`NCT03880435` - HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant	N/A
Completed	`NCT04669756` - Ovariopexy for Adhesion Prevention After Laparoscopic Removal of Endometriosis of the Pelvic Side Wall or the Ovary	N/A