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Adhesion clinical trials

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NCT ID: NCT05999162 Completed - Colorectal Cancer Clinical Trials

Mechanical Ileus in the Era of Minimally Invasive Colorectal Surgery

Start date: August 4, 2023
Phase:
Study type: Observational

The present study was to investigate if the incidence, patterns and surgical outcomes of mechanical ileus have changed in the era of minimally invasive surgery (MIS).

NCT ID: NCT05996809 Active, not recruiting - Adhesion Clinical Trials

PMCF Study for COSEAL® in Gynecologic Surgery

Start date: February 23, 2024
Phase:
Study type: Observational

The study is a single-arm, retrospective, chart review with a patient questionnaire intended to supplement the patient chart, when necessary. The population will consist of patients who underwent an index gynecologic surgery (performed at least 2 years prior to the start of the study) during which COSEAL was used as an adjunct to good surgical technique to reduce the incidence, severity, and extent of post-surgical adhesion formation. The purpose of the study is to detect the incidence of adhesion-related morbidities as measured by the proportion of adhesion-related readmissions, including reoperations in these patients. Patient charts will be reviewed to collect the data on readmissions related to adhesions, If the patient chart has no record of adhesion related readmission within approximately 2 years of the index surgery, then a patient questionnaire will be sent. A questionnaire may still be sent if a patient chart has a record of adhesion related readmission within approximately 2 years of the index surgery and further clarification is needed. The questionnaire will collect information regarding readmission or reoperation directly or possibly related to adhesions following the index gynecologic surgical procedure at a hospital or outpatient clinic other than that of the index surgery.

NCT ID: NCT05811585 Recruiting - Adhesion Clinical Trials

PMCF Study for ADEPT® in LaparoscopicGynecologic Surgery

Start date: June 26, 2023
Phase:
Study type: Observational

Postoperative adhesions develop in most patients after gynecologic surgery, likely resulting in significant morbidity, complications, and considerable increases in healthcare costs. Good surgical techniques, including a minimally invasive approach, may reduce adhesions and minimize the abovementioned complications. The agents for prevention or reduction of adhesion formation are placed inside the abdominal cavity, and especially in the pelvic cavity, which contains the female reproductive organs. ADEPT Adhesion Reduction Solution, hereinafter referred to as ADEPT, is intended for use as an intraperitoneal instillate for the reduction of adhesions following gynecological laparoscopic surgeries. The objective of this study is to evaluate the effectiveness and safety of ADEPT by detecting the incidence of adhesion-related morbidities (adhesion-related readmissions, including reoperations) after laparoscopic gynecologic surgery through a single-arm, retrospective, chart review with a patient questionnaire intended to supplement the patient chart.

NCT ID: NCT05580471 Recruiting - Adhesion Clinical Trials

A Randomized Control Study of Anti-Adhesion Agent After Colorectal Surgery

Start date: March 5, 2022
Phase: N/A
Study type: Interventional

This project is to evaluate the difference of post-operation adhesion severity and adhesion area of patient received 4DryField after colorectal surgery.

NCT ID: NCT05415059 Not yet recruiting - Adhesion Clinical Trials

LEAFix Adhesion in Healthy Volunteers

Start date: August 10, 2022
Phase: N/A
Study type: Interventional

This study compares the adhesiveness of the 3M material to be used in the final design.

NCT ID: NCT05265559 Recruiting - Adhesion Clinical Trials

Influence of Operator Factors on Succes and Survival of Indirect Restorations

Start date: October 9, 2018
Phase:
Study type: Observational [Patient Registry]

Background: Nowadays, tissue preserving, aesthetically high-quality and sustainable dentistry is more and more becoming the standard way of treatment. To reach those standards, one of the treatment options is applying a partial indirect restoration made by glass ceramics using immediate dental sealing (IDS). Using IDS, a protocol is followed to applicate a dentin bonding agent to freshly cut dentin when it is exposed during tooth preparation for indirect restorations (inlays/onlays, crowns). The preparation made for partial restorations is minimal invasive. Glass ceramic restorations have very high survival rates (90 to 100% after five years) (Morimoto et al., 2016) and glass ceramic mimics the color and structure of the tooth very well. This kind of treatment is gaining interest and increasingly applied however little information is available on the long-term effects when multiple general practitioners apply these restorations. Objectives: The main goal of this study is to evaluate partial posterior ceramic restorations with the application of an immediate dentin sealing (IDS) performed by various practitioners. Study design and population: Twenty dental practitioners, who followed a course on making ceramic partial restorations using IDS, will be asked to include patients for this study. The dental practitioners are being asked to share their data (occlusal light photo's, impression and x-rays) of twenty-five restorations they make after having the course. Restorations of individuals with a minimum age of 18 will be included. The information from pictures and impressions will be evaluated. Items to evaluate The practitioners will be interviewed to get to know in what circumstances they do their treatment. Items that are discussed are: - using rubber dam; - using magnification by means of loupes/microscope; - scheduled time for the treatment; - number of restorations after following the course. Initial data (gathered directly after treatment) will be evaluated looking at: - surface of preparation after IDS; - size of the prepared surface; - color. Follow up data will be evaluated looking at: - tooth extraction - fracture restoration - fracture tooth - secondairy caries - de-bonding - endodontic problems Outcome: Failures (fracture, de-bonding, secondairy cariës, endodontic problems) are the main outcome measurements. Description and estimation of the load and risk for the subjects: No extra intervention is performed. The dental practitioners will provide their data (i.e. impressions, occlusal light photo's) and these will be evaluated by the researchers. Follow up data will be gathered from X-rays already made for periodical oral examination (taking the caries risk into account). Summarizing, there is no extra load or risk for the patients. Studie design Prospective practice-based research, multicenter.

NCT ID: NCT05036525 Completed - Thyroid Diseases Clinical Trials

Evaluation of the Efficacy and Safety of a Hyaluronic Acid Gel in Adhesion Prevention After Open Thyroidectomy.

Start date: June 17, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to assess the safety and efficacy of HANBIO BarriGel to prevent thyroidectomy postoperative adhesions

NCT ID: NCT04837469 Completed - Adhesion Clinical Trials

Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month

Start date: January 1, 2014
Phase: N/A
Study type: Interventional

Objective: This randomized, controlled clinical study aimed to evaluate the performance of one universal adhesive applied with etch-and-rinse or self-etch strategy and one etch-and-rinse adhesive on fissure sealant retention over 24 months. Methodology: 144 sealants were placed on the permanent premolars and molars of 13 subjects. Teeth were divided into three groups SB2(control): Adper Single Bond 2, SBU-ER: Single Bond Universal/etch-and-rinse, SBU-SE: Single Bond Universal/self-etch. After the adhesive application, Fissurit FX was applied and light-cured. Clinical evaluations were done at baseline and at 1 week, 6-, 12-, 18- and 24-month recalls. Visual examination was performed on every visit for evaluation of the sealants. Evaluating criteria were: 1= completely retained; 2= partial loss; 3= total loss. The Pearson Chi-square test was used for each evaluation period.

NCT ID: NCT04669756 Completed - Surgery Clinical Trials

Ovariopexy for Adhesion Prevention After Laparoscopic Removal of Endometriosis of the Pelvic Side Wall or the Ovary

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

prospective randomized Trial comparing ovariopexy over 2, 4 or 6 days vs Placebo after surgery because of endometriosis of the pelvic side wall or the ovary or both

NCT ID: NCT04641923 Not yet recruiting - Liver Neoplasms Clinical Trials

The Efficacy of a Topical Anti-adhesive Film for Decreasing Perihepatic Adhesions in Repeat Hepatic Surgery

Start date: November 2022
Phase: N/A
Study type: Interventional

There has been an increase in the need for repeat hepatic surgery, especially for patients with colorectal liver metastasis and hepatocellular carcinoma. Adhesions at the time of repeat surgery can lead to increased operative times, higher blood loss and even increased perioperative morbidity. Not much data exists regarding use of anti-adhesion barriers at the time of index hepatectomy and their effect on adhesions at repeat hepatectomy. This randomized controlled trial aims to evaluate the effectiveness of the use of a hyaluronan and cellulose based antiadhesive topical film at index hepatectomy in reducing perihepatic adhesions at the time of repeat hepatic surgery.