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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT03654144
Other study ID # DINADEN
Secondary ID
Status Not yet recruiting
Phase Phase 4
First received
Last updated
Start date November 2018
Est. completion date March 2020

Study information

Verified date August 2018
Source Assiut University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Adenomyosis was first described as endometrial glands in the myometrium of the uterus. The current definition of adenomyosis is provided in 1972 'the benign invasion of endometrium into the myometrium, producing a diffusely enlarged uterus which microscopically exhibits ectopic non-neoplastic, endometrial glands and stroma surrounded by the hypertrophic and hyperplastic myometrium


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 100
Est. completion date March 2020
Est. primary completion date December 2019
Accepts healthy volunteers No
Gender Female
Age group 40 Years and older
Eligibility Inclusion Criteria:

- symptomatic adenomyosis

- irregular menstrual bleeding and dysmenorrhea .

Exclusion Criteria:

- asymptomatic patients -

- non-lactating patient

- not desire for pregnancy

- no hormonal treatment more than 6 month even contraception e.g IUD

- no focal lesion of uterus (malignancy ,fibroid or adenxal mass )

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Dienogest
oral tablets
Combined Oral Contraceptive
oral tablets

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Assiut University

Outcome

Type Measure Description Time frame Safety issue
Primary The mean pain score after receiving treatment assessment by visual analog scale 6 months
See also
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Active, not recruiting NCT06223464 - Evaluation of the Relationship Between Adenomyosis and Elastographic Properties of the Cervix
Completed NCT05419414 - The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis N/A
Recruiting NCT05152667 - Ambispective Study to Assess the Effect of Pretreatment With a Levonorgestrel-Releasing Intrauterine System Versus Oral Progestin
Completed NCT02192606 - Does 3D Laparoscopy Improve Vaginal Cuff Suture Time? N/A
Completed NCT01992718 - What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography Early Phase 1
Recruiting NCT02495311 - The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms
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Completed NCT01821001 - Vaginal Bromocriptine for Treatment of Adenomyosis Phase 1
Recruiting NCT04295109 - Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function N/A
Recruiting NCT04356664 - Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis Phase 2/Phase 3
Active, not recruiting NCT04791033 - Quality of Life After Hysterectomy (AdenoQOL)