Clinical Trials Logo
  1. Home
  2. Adenoma
  3. NCT02353533

Endoscopic Full-thickness REsection of Residual Colorectal Lesions - The FiRE Study — FiRE  

Adenoma Clinical Trial

Clinical Trial Summary

Adenomatous lesions of the colon are premalignant lesions which have the potential to develop cancer. Therefore adenomas should be resected endoscopically (endo- mucosa resection, EMR). EMR is conducted after submucosal injection of saline which allows to lift the desired lesion prior to resection. In some cases EMR is complicated due to incomplete or failed lifting after the injection of saline. This so- called "non- lifting" sign is a predictor for malignancy of the lesion. Difficult- to- lift polyps are also difficult- to- resect. A higher proportion of these lesions fail to be resected completely using the EMR technique.

Alternatively, an over- the- scope full- thickness resection device (FTRD) can be used in order to resect colonic lesions. The FTRD technique has been described elsewhere (Schmidt et al. Gastroenterology 2014; 147: 740-742.e2). No comparative data exists until now on the performance of FTRD resection compared to standard EMR resection of difficult- to- resect colon adenomas.

In this study the investigators aim to compare the success of FTRD versus EMR of difficult- to- resect adenomatous lesions (≤ 20 mm).

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02353533
Study type Interventional
Source Technische Universität München
Contact Peter Klare, MD
Phone +49 89 4140 2251
Email peter.klare@lrz.tum.de
Status Recruiting
Phase N/A
Start date January 2015
Completion date December 2017
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05551052 - CRC Detection Reliable Assessment With Blood
Recruiting NCT02545699 - Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy N/A
Completed NCT01802008 - Comparison of Adenoma Detection Miss Rates at Colonoscopy Associated With Different Withdrawal Times N/A
Recruiting NCT01211132 - Cap Assisted Colonoscopy for the Detection of Colon Polyps N/A
Completed NCT04287335 - Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China
Not yet recruiting NCT06398418 - R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors Phase 1
Recruiting NCT05362344 - Colorectal Cancer Screening in Cystic Fibrosis
Completed NCT03268200 - The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy N/A
Recruiting NCT04591145 - Multi-center Validation of a Deep Learning Based Bowel Preparation Evaluation System
Completed NCT02978664 - The Impact of Distraction on Adenoma Detection Rate N/A
Completed NCT00018551 - Chemoprevention With Folic Acid Phase 2
Recruiting NCT05594576 - Comparison of the ENDOCUFF VISION® Endoscopy Cap Coupled With GI GENIUS™ Artificial Intelligence Compared to Each Device Alone in Improving Colonic Adenoma Detection Rate During Colonoscopy N/A
Not yet recruiting NCT04135716 - A Multicenter Study Evaluating the Effectiveness of Endo.Angel in Improving the Quality of Colonoscopy N/A
Recruiting NCT02288962 - Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas Phase 3
Recruiting NCT02552017 - Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities N/A
Completed NCT02066064 - G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist N/A
Completed NCT01749722 - Safety and Efficacy of the NaviAid™ G-Eye System During Colonoscopy N/A
Completed NCT01485133 - Water Method Colonoscopy in Patients With Prior Surgery N/A
Withdrawn NCT01546246 - Water Method in Patients With Incomplete Colonoscopy N/A
Withdrawn NCT01546220 - Water Method in Elder Patients With Unsedated Colonoscopy N/A