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Adenoma clinical trials

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NCT ID: NCT03516747 Withdrawn - Hypercalcemia Clinical Trials

Preoperational Fine Needle Aspiration of Pathological Parathyroid Gland

Start date: June 9, 2018
Phase: N/A
Study type: Interventional

Identification and localization of pathological parathyroid gland before parathyroidectomy is traditionally done by a combination of two methods: ultrasound and sestamibi scan. The investigators would like to show that one exam that includes ultrasound and fine needle aspiration of the parathyroid gland for parathyroid hormone level is as accurate as the traditional method.

NCT ID: NCT03515603 Terminated - Pituitary Adenoma Clinical Trials

Endocrine Outcome of Surgery for Pituitary Adenoma

Start date: May 10, 2018
Phase: N/A
Study type: Interventional

Prospective and randomized compare between microsurgical and endoscopic transsphenoidal MRI assisted resection of pituitary adenomas.

NCT ID: NCT03506321 Completed - Colorectal Cancer Clinical Trials

Comparison of the Benefit of Chromoendoscopy in Addition to High Definition White Light and Narrow Band Imaging for the Prediction of Submucosal Invasive Cancer in Colonic Lesions

LANS
Start date: February 7, 2018
Phase: N/A
Study type: Interventional

To compare the incremental benefit of chromoendoscopy in addition to high definition white light and narrow band imaging in predicting submucosal invasion within laterally spreading lesions in the colon and in determining the presence of residual or recurrent adenoma at the post endoscopic resection scar

NCT ID: NCT03501849 Completed - Colorectal Cancer Clinical Trials

Cold Snare Polypectomy

Cold-Snare
Start date: May 15, 2018
Phase: N/A
Study type: Interventional

During colonoscopy, the endoscopist will document prospectively all polyps detected and note the size, location and morphology. Polyps of 4-20 mm will be removed only in accordance with the method the cold snare. Afterwards, the remaining tissues could be observed with an imaging technology called Optivista with an injection of 10-50 ml of saline solution (if required) to improve visibility of the tissues. The endoscopist will continue to remove the remaining polyp tissue (with a snare or forceps) until there are no more visible polyp tissues. Biopsies from the polyp resection site will be sent to the laboratory for analysis to confirm the complete resection.

NCT ID: NCT03494543 Completed - Clinical trials for Familial Adenomatous Polyposis

Endoscopic Papillectomy for Ampullary Adenomas

Papillectomy
Start date: January 1, 2005
Phase:
Study type: Observational

In this single-center experience we retrospectively evaluated principal clinical outcomes of endoscopic papillectomy in all patients referred to our unit. The same evaluation was then performed dividing sproradic ampullary adenoma from familial adenomatous polyposis associated adenomas, and resulting outcomes were compared.

NCT ID: NCT03486418 Active, not recruiting - Clinical trials for Colorectal Neoplasms

European Serrated Adenoma Classification Score

ESCO
Start date: April 1, 2018
Phase:
Study type: Observational

The aim of the study is to develop a score system in order to differentiate adenomatous polyps, hyperplastic polyps and serrated adenomas on the basis of optical features. Endoscopic images of colorectal polyps will be collected from a prospectively managed database. Histopathological diagnoses are available for all polyps. Histopathological diagnoses serve as gold standard in this study. In the first phase of the study optical features of serrated adenomas are extracted from the database. Discriminators are then defined on the basis of the extracted features. In the second phase a test set of high quality pictures are provided to both novices and experts of colorectal endoscopy. Participants are asked to use the above named discriminators in order to rate pictures and to classify polyps into three classes (adenomatous polyps, hyperplastic polyps and serrated adenomas). In the third phase of the study accuracy of optical bases diagnoses is calculated by comparing optically derived diagnoses with histopathological diagnoses (gold standard).

NCT ID: NCT03474237 Enrolling by invitation - Pheochromocytoma Clinical Trials

A Prospective Cohort Study for Patients With Adrenal Diseases

Start date: October 1, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate the pathologic features, complications, and prognostic factors of functioning adrenal adenoma and suggest follow-up algorithms for adrenal incidentaloma.

NCT ID: NCT03471793 Recruiting - Colon Polyp Clinical Trials

The Australian Colonic Large Sessile Lesion Endoscopic Resection Study

ACE
Start date: February 24, 2017
Phase:
Study type: Observational

A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis

NCT ID: NCT03471403 Recruiting - Clinical trials for Familial Adenomatous Polyposis

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis

COPDA
Start date: October 10, 2017
Phase:
Study type: Observational

The purpose of this study is to collect prospective observational data regarding patients with diagnosed Familial Adenomatous Polyposis (FAP) undergoing cold snare polypectomy for duodenal adenomas

NCT ID: NCT03469622 Recruiting - Adenoma Clinical Trials

EndoRings Colonoscopy for Adenoma Detection

ER
Start date: March 27, 2018
Phase: N/A
Study type: Interventional

Adenoma detection rate (ADR) in colon cancer screening is most important for avoiding colon cancer development. Recent studies suggest a benefit of endoscopic devices attached to the distal tip of the colonoscope for improving the ADR. This work is the first GERMAN randomized controlled trial comparing standard colonoscopy with EndoRIngs-assisted colonoscopy. EndoRings is a new FDA approved device that is attached to the distal tip of the colonoscope. Better Polyp detection is suspected by flattening the mucosal folds during withdrawal