Comparison of HT Concomitant With RT vs RT Alone in Patients With a Detectable PSA After Prostatectomy — GETUG-AFU22

Adenocarcinoma of Prostate Clinical Trial

Official title:
A Multicenter Randomised Phase II Study Comparing the Efficiency of a HT Concomitant With RT vs RT Alone in the Salvage of Patients With a Detectable PSA After Prostatectomy

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to select the best therapeutic strategy in studying the effectiveness of the association of a short duration hormonal therapy and radiotherapy compared with radiotherapy alone, in patients with a detectable PSA after radical prostatectomy.

Clinical Trial Description

Study the effectiveness of the association of a short duration hormonal therapy by degarelix (Firmagon ®) and radiotherapy, with radiotherapy alone on survival without events in the treatment of detectable PSA after radical prostatectomy. 122 patients should be included over a period of 2 years. Patients will be treated according to the following scheme: - Arm A (61 patients) : Pelvic Radiotherapy: 46 Gy and prostate only boost up to 66 Gy - Arm B (61 patients) : Arm A + hormonal therapy by degarelix during 6 months ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01994239
Study type	Interventional
Source	UNICANCER
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	December 2012
Completion date	March 2025

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