Clinical Trials Logo
  1. Home
  2. Acute Respiratory Insufficiency
  3. NCT03358043

Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in Wales — PANDORAWALES  

Acute Respiratory Insufficiency Clinical Trial

Official title:
Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in Wales

Clinical Trial Summary

This study is aimed to establish the epidemiological chacacteristics and clinical outcomes of mechanically ventilated patients with acute hypoxemic respiratory failure admitted in a network of hospitals from Wales (U.K.).

Clinical Trial Description

The present study is aimed to establish the epidemiological characteristics and clinical outcomes of adult mechanically ventilated patients with acute hypoxemic respiratory failure [defined as a PaO2/FiO2 ≤300 mmHg on positive end-expiratory pressure (PEEP) of 5 cmH2O or more and FiO2 of 0.3 or more] admitted in a network of hospitals from Wales (U.K.). Although there are few previous published observational studies examining the incidence and mortality of patients with acute respiratory failure and ARDS, there are no studies specifically assessing the epidemiological characteristics, patterns of ventilation and clinical outcomes in patients with acute hypoxemic respiratory failure in the current era of lung protective ventilation. This study will be done simultaneously with the PANDORA (NCT03145974) in Spain.

The study is aimed to improve the knowledge on the epidemiology and outcome of ventilated patients, to identify the percentage of patients developing ARDS under the current definition, to validate a bedside scoring system for stratification of lung severity, and to examine the prognosis of hypoxemic respiratory failure, and risk factors associated with fatal outcome. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03358043
Study type Observational
Source Dr. Negrin University Hospital
Contact
Status Completed
Phase
Start date October 1, 2017
Completion date August 31, 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT02592512 - NIV-NAVA vs NIV-PS/PC in Respiratory Insufficiency N/A
Completed NCT00835809 - Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic N/A
Recruiting NCT04791501 - Prevalence AND Outcome of Acute Hypoxemic Respiratory fAilure in CHILDren (PANDORA-CHILD)
Completed NCT01931228 - Mechanical Insufflation-Exsufflation in Preventing Post Extubation Respiratory Failure in Patient With Critical Care Neuromyopathy N/A
Completed NCT03145974 - Prevalence and Outcome of Acute Hypoxemic Respiratory Failure
Completed NCT01901497 - Pharmacokinetics of Nebulized Amikacin in Non Invasive Ventilated Healthy Volunteers. N/A
Completed NCT00686257 - Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure N/A
Completed NCT02939963 - Ventilation Strategies During Spontaneous Breathing Trial N/A
Completed NCT04346693 - An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19 Phase 3