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Clinical Trial Summary

A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient. The most prevalent kind of asynchrony was ineffective triggering (68%), followed by delayed termination (19%), double triggering (4%) and premature termination (3%). Asynchrony between the patient and ventilator increased considerably with decreasing levels of peak inspiratory pressure, positive end-expiratory pressure, and set frequency.Despite this, more asynchrony categories exist, and there is no widely accepted categorization. Major asynchronies, however, include auto trigger, ineffective effort, and double trigger, while minor asynchronies include early/late cycle, trigger delay, and spontaneous breaths during a mandatory breath. This study aims to compare the safety and efficacy of a closed-loop synchronization controller with conventional control of synchronization during invasive mechanical ventilation of spontaneous breathing of pediatric patients in a pediatric intensive care unit (PICU).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05731024
Study type Interventional
Source Dr. Behcet Uz Children's Hospital
Contact Hasan Agin, Professor
Phone +905362013162
Email hasanagin@gmail.com
Status Recruiting
Phase N/A
Start date February 6, 2023
Completion date December 30, 2024

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