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Acute Otitis Externa clinical trials

View clinical trials related to Acute Otitis Externa.

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NCT ID: NCT03196973 Recruiting - Clinical trials for Acute Otitis Externa

Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Acute Otitis Externa

Start date: July 22, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if a combination of an antibiotic plus a corticosteroid is safe and effective in treating AOE

NCT ID: NCT02918773 Completed - Acute Otitis Media Clinical Trials

Pediatric Emergency Department Smartphone Otoscope Study (PED-Oto)

Start date: October 15, 2016
Phase: N/A
Study type: Interventional

Acute otitis media (AOM), defined as acute inflammation in the middle ear, is a leading cause of health encounters and antimicrobial prescriptions in children worldwide. Diagnosis of AOM is often dependent on a brief view of the tympanic membrane in an uncooperative child's ear canal. As a consequence, AOM may be inappropriately diagnosed when visualization of the tympanic membrane (ear drum) is not optimal. Improved methods for visualizing the tympanic membrane including capturing still images and recording video of the ear exam would be beneficial in the diagnosis and management of otic complaints, including acute and chronic otitis media. Use of a smartphone otoscope has the potential to optimize clinician ability to manage otic complaints, visualize the tympanic membrane, and support antimicrobial stewardship. This study will be conducted as a randomized control study in two affiliated children's hospital emergency departments. Twenty volunteer clinicians will be randomly assigned to use either a smartphone otoscope or a conventional otoscope for all otic examinations for a 6-month period.

NCT ID: NCT02801370 Completed - Clinical trials for Acute Otitis Externa

Phase 3 Study of OTO-201 in Acute Otitis Externa

Start date: June 2016
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized, double-blind, sham-controlled, multicenter, Phase 3 study in which eligible subjects with acute otitis externa (AOE) will be randomized to receive a single administration of either 12 mg OTO-201 or Sham-Control (empty syringe) to the external auditory canal of the affected ear(s).

NCT ID: NCT02216071 Recruiting - Clinical trials for Acute Otitis Externa

Comparative Efficacy and Safety of Two Ciprofloxacin 0.3% and Dexamethasone 0.1% Formulations in Subjects With Acute Otitis Externa

Start date: July 2014
Phase: Phase 3
Study type: Interventional

The purpose of the study is to demonstrate the clinical therapeutic non-inferiority of EXL CDOS to commercially available Ciprofloxacin 0.3% and Dexamethasone 0.1% Sterile Otic Suspension (Ciprodex®, Alcon) in the treatment of acute otitis externa (AOE) when administered twice daily for 7 days.

NCT ID: NCT01584271 Recruiting - Clinical trials for Acute Otitis Externa

Study of Ear Comfort Ear Drops to Treat AOE Cases Compared to DexOtic & Otidin(R)

Start date: July 2011
Phase: Phase 2
Study type: Interventional

Phase II 3 arm double blinded clinical study, to evaluate pain killing and healing time of Botanical Ear Drops, Ear Comfort™, in Severe External Ear Infection (AOE) patients in comparison to Dex-Otic® and Otidin®. Study Outcome (hypothesis): if Ear Comfort™ proves to perform as well as Dex-Otic, then ENT's and family doctors will have a botanical non-antibiotic product that does not promote the formation of antibiotic-resistant infections and may be given to anti-biotics sensitive patients. Ear comfort™ is pharmacologically stable for at least 3 years on the shelves.

NCT ID: NCT01535599 Completed - Clinical trials for Acute Otitis Externa

Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study was to demonstrate the superiority of AL-60371, 0.3% Otic Suspension relative to AL-60371 Vehicle based on clinical cures at test-of-cure (TOC) for the treatment of acute otitis externa (AOE).

NCT ID: NCT01535560 Completed - Clinical trials for Acute Otitis Externa

Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa

Start date: April 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study was to demonstrate superiority of AL-60371 relative to Vehicle based on clinical cures at test-of-cure (TOC) for the treatment of acute otitis externa (AOE).

NCT ID: NCT01447017 Completed - Clinical trials for Acute Otitis Externa

A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis

Start date: November 2011
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate safety and tolerability of DPK-060 2% ear drops compared to placebo for DPK-060 ear drops in patients with acute external otitis. The secondary objectives are to evaluate clinical cure and microbiological growth following treatment with DPK-060 2% ear drops compared to placebo for DPK-060 ear drops.

NCT ID: NCT00961675 Completed - Clinical trials for Acute Otitis Externa

FST-201 in the Treatment of Acute Otitis Externa

Start date: August 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the efficacy of FST-201 compared to Ciprodex in the treatment of acute otitis externa. This study will be conducted at one site, the LBJ Tropical Medical Center, Department of Otolaryngology, in Pago Pago, American Samoa.

NCT ID: NCT00945802 Terminated - Clinical trials for Acute Otitis Externa

FST-201 In The Treatment of Acute Otitis Externa

Start date: July 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the efficacy of FST-201 compared to Ciprodex in the treatment of acute otitis externa. This trial is designed to enable filing of a New Drug Application in support of FST-201 for the indication of acute otitis externa.