Acute Myeloid Leukemia Clinical Trial
Official title:
A Phase I/II Clinical Trial of RC1012 Injection for the Prevention of Relapse in AML Patients After Allogeneic Hematopoietic Stem Cell Transplantation
To evaluate the safety and tolerability of RC1012 injection infusion in AML Patients after Allo-HSCT
This study aims to evaluate the safety and tolerability of RC1012 injection infusion in AML Patients after Allo-HSCT. DNT cells are mature T lymphocytes that comprise 3-10% of T cells in human peripheral blood mononuclear cells (PBMC). Allo-DNT cells from healthy donors have been proved to be safe and demonstrated potent cytotoxicity against AML blasts from AML patients in preclinical and preliminary clinical studies. Allo-DNT cells will be collected from healthy donors (NO MHC match needed) and infused into patients. The drug for this study is an off-the-shelf product. Patients DO NOT need to wait for the cell manufacturing. ;
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