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Clinical Trial Summary

This is research study to find out if a drug called ADCT-301 is safe and to look at how patients respond to the study drug after an allogeneic transplantation. ADCT-301 will be administered on Days 1, 8 and 15 with blood tests following study drug infusion. Patients will have a bone marrow biopsy at the end of cycle 2/before cycle 3 to see how they are responding to the study drug. Patients will be followed for approximately every 12 weeks from the last disease assessment for up to 1 year from completion of therapy. There are risks to this study drug. Some risks include: decrease in certain blood cells, weight loss, loss of appetite, rash and Guillain-Barre syndrome, where the immune system attacks and damages nerves.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04639024
Study type Interventional
Source Duke University
Contact
Status Terminated
Phase Phase 2
Start date December 7, 2021
Completion date November 3, 2022

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