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Clinical Trial Summary

This research study tests a new medicine for mobilizing stem cells so they can be collected and used for allogeneic stem cell transplant for treatment of hematological malignancies. MGTA-145, the new medicine, will be given with plerixafor.


Clinical Trial Description

This is a Phase II, open-label, multicenter, prospective study of MGTA-145 + plerixafor mobilized HLA-matched sibling and matched unrelated donor allografts for myeloablative hematopoietic stem cell transplantation (HSCT) in recipients with hematological malignancies. Donors will undergo 1 or 2 days of mobilization and apheresis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04762875
Study type Interventional
Source Ensoma
Contact
Status Terminated
Phase Phase 2
Start date June 16, 2021
Completion date March 14, 2022

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