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Acute Kidney Injury clinical trials

View clinical trials related to Acute Kidney Injury.

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NCT ID: NCT03877133 Completed - Clinical trials for Liver Transplant; Complications

Association of Intraoperative Renal Regional Oxygen Saturation and Acute Kidney Injury

Start date: March 11, 2019
Phase: N/A
Study type: Interventional

This study is a prospective observational study of a single cohort of the patients who will undergo a scheduled living donor liver transplantation. The investigators attempt to evaluate the association of intraoperative renal regional oxygen saturation and acute kidney injury in patients undergoing living donor liver transplantation. Near-infrared spectroscopy sensor will be attached to the skin near bilateral kidney areas in all patients and renal regional oxygen saturation will be monitored during the operation. Renal regional oxygen saturation (rSO2) of the patients who developed acute kidney injury postoperatively will be compared with rSO2 of the patients who did not.

NCT ID: NCT03877081 Recruiting - Sepsis Clinical Trials

Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients

Start date: January 4, 2019
Phase: Phase 3
Study type: Interventional

Septic acute kidney injury is a condition associated with highly related to inflammatory molecules. Prebiotics and probiotics have shown to improve inflammatory cascade in animal model; In this study, the investigators propose the use of probiotics to improve the clinical evolution of septic acute kidney injury patients.

NCT ID: NCT03860545 Completed - Acute Kidney Injury Clinical Trials

New Markers of Cardiac Surgery Related Acute Kidney Injury.

Start date: January 2, 2018
Phase:
Study type: Observational

Cardiac surgery related acute kidney injury (CS-AKI) is a clinical problem associated with a cardiopulmonary bypass used during cardiac surgery procedures. In this study the investigators will assess the biochemical markers of acute kidney injury such as ischemia modified albumin (IMA) or urinary excreted of brush-border enzymes of the proximal renal tubules perioperatively. There has been no official recommendations toward routine use of analysed biomarkers.

NCT ID: NCT03856723 Recruiting - Acute Kidney Injury Clinical Trials

Predicting Outcomes of Cardiac Surgery-associated Acute Kidney Injury Using Biomarkers At Initiation of RRT

Start date: March 1, 2019
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to verify the prognostic value of functional kidney biomarkers on survival and renal function recovery in cardiac surgery patients with acute kidney injury.

NCT ID: NCT03854825 Completed - Acute Kidney Injury Clinical Trials

Neutral Endopeptidase for Early Detection of Acute Kidney Injury After Cardiac Surgery

NEPAKI-CS
Start date: October 30, 2016
Phase:
Study type: Observational

The investigators want to investigate if the urinary biomarker neprilysin can identify cardiac surgical patients suffering from postoperative AKI within 24 hours.

NCT ID: NCT03846258 Withdrawn - Acute Kidney Injury Clinical Trials

High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy

Start date: May 1, 2019
Phase: Phase 4
Study type: Interventional

Researchers are trying to determine which dialysis solution, low bicarbonate fluid (22 mmol/L) or high bicarbonate fluid (32 mmol/L), is better in subjects with acute kidney injury (acute kidney failure) and metabolic acidosis that are admitted to the intensive care unit and require continuous renal replacement therapy (also known as continuous dialysis).

NCT ID: NCT03836742 Completed - Acute Kidney Injury Clinical Trials

HEmoFiltration With Citric Acid Anticoagulation

HEFCAA
Start date: August 11, 2015
Phase:
Study type: Observational

Prospective observational study of all consecutive cardio-vascular surgical patients treated with post-dilution hemofiltration with regional citrate anticoagulation as first-choice anticoagulation method. The filter life-span was assessed in the context of postoperative cardiac surgical antithrombotic prophylaxis. Reasons for termination of hemofiltration sessions were assessed. The second aim of this study was to assess the influence ACD-A based anticoagulation protocol on acid-base and ion homeostasis in cardiac surgical patients with acute renal failure.

NCT ID: NCT03830450 Not yet recruiting - Clinical trials for Acute Kidney Injury (Nontraumatic)

Biomarkers of Acute Kidney Injury in Cardiac Surgery

AKIrisk
Start date: December 1, 2020
Phase:
Study type: Observational [Patient Registry]

Acute kidney injury (AKI) is the most common complication in patients after cardiac surgery. An usual estimation of risk for AKI is estimation of serum creatinine, which is unreliable indicator of AKI risk. Because of that, today different biomarkers are investigated to predict incidence for development AKI after cardiac surgery. This investigation will try to find potentially risk patients for developing AKI after cardiac surgery by using conventional markers (creatinine, glomerular filtration rate) in perioperative period comparing with two different biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and growth differentiation factor 15 (GDF-15) which are proven markers in patients with increased risk for AKI development.

NCT ID: NCT03817281 Withdrawn - Sepsis Clinical Trials

Collective Accuryn Physiologic Signals and Signatures

CAPSS
Start date: March 29, 2020
Phase:
Study type: Observational [Patient Registry]

The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device. Physiologic data measurements will be collected from enrolled subjects using electronic health records and data streams via the Accuryn Monitoring System. Analysis of these data has the potential to be able to acutely guide resuscitation and monitor trends for emerging critical conditions.

NCT ID: NCT03810833 Completed - Acute Kidney Injury Clinical Trials

Tolerability and Background Fluorescence of the MediBeacon Transdermal GFR Measurement System

Start date: September 16, 2019
Phase: N/A
Study type: Interventional

This study is designed to evaluate background fluorescence of participants of different ages, gender, and skin color. In addition, 48-hour tolerability of the sensor and adhesive will be evaluated.