Diagnostic Performance of Coronary Calcification Detection on CT Scan

Acute Coronary Syndrome Clinical Trial

— Calci-DT  

Official title:

Diagnostic Performance of Coronary Calcification Detection on CT Scan

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05538117
• Other study ID #: 8697
• Status: Completed
• Start date: August 18, 2022
• Est. completion date: October 18, 2023

Study information

• Verified date: December 2023
• Source: University Hospital, Strasbourg, France
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial infarction to chest pain during an anxiety attack. Efficient triage of patients is therefore a crucial issue for emergency physicians in order not to ignore an acute coronary event requiring early and specific management.

The investigators seek to evaluate whether a diagnostic strategy based on a thoracic CT scan to rule out coronary calcifications and a single troponin assay can exclude an acute coronary event with sufficient accuracy compared to usual management.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: October 18, 2023
• Est. primary completion date: August 18, 2023
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion criteria:

• Adult patient (=18 years old)

• Patient admitted to the emergency room of the Nouvel Hôpital Civil in Strasbourg between 06/01/2021 and 12/31/2021 and presenting with typical chest pain <30min or atypical symptoms but non-eliminable cardiac origin.

• Patient with an initial assessment within the norms (ECG not modified, first troponin negative) and having performed a chest CT scan

• Patient who has not expressed his opposition to the reuse of his data for scientific research purposes.

Exclusion criteria:

• Patient who has expressed his opposition to the retrospective reuse of his data for scientific research purposes

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Calcinosis

Locations

Country	Name	City	State
France	Service d'accueil des urgences - CHU de Strasbourg - France	Strasbourg

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ability of scan CT to detect coronary calcifications in patients presenting with thoracic pain to the emergency department	Presence on the scanner of calcifications 30 minutes after onset of pain	30 minutes after onset of pain