Localization of Microvascular Dysfunction

Status Completed

Clinical Trial Summary

Microvascular dysfunction is an independent predictor of poor prognosis. Such response in the culprit vessel is common even after successful revascularization. This study investigated whether the microvascular dysfunction differed between culprit and non-culprit vessels in patients with acute coronary syndrome (ACS) who underwent percutaneous coronary intervention (PCI).

Clinical Trial Description

The prospective study included 115 patients with ACS. In this study, after successful PCI, culprit and non-culprit intracoronary hemodynamic measurements were performed and repeated at 6-month follow-up. 13N-ammonia positron emission tomography (PET) was performed at 6-month follow-up visit to determine absolute myocardial blood flow (MBF). The resistance values of each vessel were calculated using the coronary pressure data and the MBF values obtained from 13N-ammonia PET data. Such physiological measures were compared between culprit and non-culprit vessels in baseline and 6-month follow-up. ;

Study Design

Related Conditions & MeSH terms

Acute Coronary Syndrome

Clinical Trial Details

NCT number	NCT04169516
Study type	Observational [Patient Registry]
Source	Dong-A University
Contact
Status	Completed
Phase
Start date	December 1, 2014
Completion date	November 10, 2019

View Details

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