Acquired Brain Injury Clinical Trial
Official title:
COgnitive REhabilitative Treatments in Pediatric Patients With Severe Acquired Brain Injury From Vegetative State to Functional Recovery
Acquired brain lesions (GCLA) represent one of the most important cause of disability and mortality during the pediatric age, also in the western Countries. The important medical progresses of the last decade in the medical field have increased the percentages of survival, also in the most severe clinical pictures. On the other hand, a brain lesion reported in the first years of life presents with a more dramatic impact on the cognitive and neurological development of the patients and it can significantly interfere with the same quality of their life. Recent studies suggest that a brain damage in this stage of the life is related to more persistent sequelae in comparison of the same lesion reported by an adult patient, because of the neurological immaturity at the moment of the insult. Furthermore, in most cases, the brain lesion is related not only to motor and sensorial deficits but also to very important behavioral and cognitive problems, that can arise immediately after the acute phase, or also several years after the pathological event.
The aims of the present study are: 1. To contribute to the adaptation of the Italian version of the Coma Recovery Scale (CRS-R) for the pediatric age, with specific differentiation and taking into account the age of the patients and the specific learning that characterize each developmental stage; 2. As regards the patients with an adequate cognitive profile, to compare the effectiveness of a traditional multifunction neuropsychological treatment (cognitive functions are stimulated at the same time) vs a sequential treatment (cognitive functions are stimulated step by step). ;
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