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NCT05471388 Clinical Trial

Assessment of Serum Asprosin Level in Male Patients With Acne Vulgaris

Acne Vulgaris Clinical Trial

Official title:
Assessment of Serum Asprosin Level in Male Patients With Acne Vulgaris

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05471388
Other study ID # Soh-Med-22-07-06
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date July 18, 2022
Est. completion date January 18, 2023

Study information
Verified date July 2022
Source Sohag University
Contact Esraa A Hamoda, resident
Phone 01007911703
Email esraaabdelazeem@med.sohag.edu.eg
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Subject of interest is to evaluate serum level of asprosin in male patients with acne vulgaris, demonstrate the relation between acne vulgaris severity and level of asprosin in these patients & the relation between metabolic syndrome in acne vulgaris and level of asprosin.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 72
Est. completion date January 18, 2023
Est. primary completion date January 18, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 18 Years and older
Eligibility Inclusion Criteria: - Acne vulgaris male patients (>18 years) will be included. Exclusion Criteria: - Age <18 years. - Females. - Patients with other inflammatory skin disorders. - Patients with associated systemic diseases. - Current or previous treatment with isotretinoin in the last 3 month ,anti-inflammatory drugs, systemic antibiotics, androgen or anti androgen therapy, and steroid therapy). - Patients known on treatment of diabetes, hypertension and dyslipidemia. - Athletes. - Patient refusal.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• serum asprosin
assessment of serum asprosin by a commercially available double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) kit.

Locations
Country Name City State
Egypt Sohag University Hospital Sohag

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Hong T, Li JY, Wang YD, Qi XY, Liao ZZ, Bhadel P, Ran L, Yang J, Yan B, Liu JH, Xiao XH. High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome. Int J Endocrinol. 2021 Mar 2;2021:6622129. doi: 10.1155/2021/6622129. eCollection 2021. — View Citation

Kovács D, Fazekas F, Oláh A, Törocsik D. Adipokines in the Skin and in Dermatological Diseases. Int J Mol Sci. 2020 Nov 28;21(23). pii: E9048. doi: 10.3390/ijms21239048. Review. — View Citation

Nagpal M, De D, Handa S, Pal A, Sachdeva N. Insulin Resistance and Metabolic Syndrome in Young Men With Acne. JAMA Dermatol. 2016 Apr;152(4):399-404. doi: 10.1001/jamadermatol.2015.4499. — View Citation

Rocha MA, Bagatin E. Adult-onset acne: prevalence, impact, and management challenges. Clin Cosmet Investig Dermatol. 2018 Feb 1;11:59-69. doi: 10.2147/CCID.S137794. eCollection 2018. Review. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Assess serum asprosin level in male patients with acne vulgaris. Assess serum asprosin level in male patients with acne vulgaris. 6 months
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