Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow

Accident Caused by Snow Avalanche Clinical Trial

— GasProp  

Official title:

Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT05262894
• Other study ID #: 2022-Bradler
• Status: Enrolling by invitation
• Phase: N/A
• Start date: February 7, 2022
• Est. completion date: May 31, 2025

Study information

• Verified date: February 2022
• Source: Czech Technical University in Prague
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study is aimed at investigation of respiratory gases propagation in snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow.

Description:

The study is aimed at investigation of respiratory gases (oxygen and carbon dioxide) propagation in the simulated avalanche snow. The study involves volunteers breathing into the snow whereas concentrations of gases are measured at various positions in the snow. A special apparatus was created for sampling and measurement of gas concentrations and to assure stable geometry of the experiment required for data evaluation.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 50
• Est. completion date: May 31, 2025
• Est. primary completion date: May 31, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• healthy and fit volunteers, classified as The American Society of Anesthesiologists class I

• without a smoking history

Exclusion Criteria:

• Tiffeneau Index less than 0.70

• any cardiovascular or respiratory condition

Related Conditions & MeSH terms

• Accident Caused by Snow Avalanche
• Respiratory Aspiration

Intervention

Other:
• extreme hypercapnia induced by ventilation insufficiency
Re-breathing of gas by breathing into the simulated avalanche snow

Locations

Country	Name	City	State
Czechia	Czech Technical University, Faculty of Biomedical Engineering	Kladno

Sponsors (1)

Lead Sponsor	Collaborator
Czech Technical University in Prague

Country where clinical trial is conducted

Czechia, 

References & Publications (2)

Roubík K, Sieger L, Sykora K. Work of Breathing into Snow in the Presence versus Absence of an Artificial Air Pocket Affects Hypoxia and Hypercapnia of a Victim Covered with Avalanche Snow: A Randomized Double Blind Crossover Study. PLoS One. 2015 Dec 14;10(12):e0144332. doi: 10.1371/journal.pone.0144332. eCollection 2015. — View Citation

Roubik K, Sykora K, Sieger L, Ort V, Horakova L, Walzel S. Perlite is a suitable model material for experiments investigating breathing in high density snow. Sci Rep. 2022 Feb 8;12(1):2070. doi: 10.1038/s41598-022-06015-y. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The length of breathing	Time to termination of the breathing experiment due to the decision of the tested subject, or determined by high end-tidal carbon dioxide value or by the order by the clinician assessing the health status of the subjects.	Continuously within up to 20 minute interval from the beginning of the breathing experiment