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Acceptability clinical trials

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NCT ID: NCT06384326 Completed - Acceptability Clinical Trials

Parental Perceptions and Acceptance of Silver Diamine Fluoride in Spain and Italy

SDF
Start date: September 1, 2020
Phase:
Study type: Observational [Patient Registry]

Assessing parental aesthetic acceptability of Silver Diamine Fluoride (SDF) staining is crucial for its potential implementation in paediatric dentistry. This study represents the third part of a wider project initially focused on evaluating SDF aesthetic acceptability in Italy, then comparing it between Spanish and Italian parents

NCT ID: NCT06374316 Active, not recruiting - Feasibility Clinical Trials

Air Purifiers in Classrooms for Infection Control - a Pilot Study

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

This study aims to investigate the acceptability and feasibility of deploying air purifiers equipped with HEPA (high-efficiency particulate air) filters in classrooms, to study air purifiers as an infection control measure. It will also evaluate the direct effect of air purifiers on air quality, comparing ceiling-mounted purifiers, portable purifiers and no purifier.

NCT ID: NCT06320964 Completed - Feasibility Clinical Trials

The TARANG Intervention

TARANG Pilot
Start date: July 14, 2023
Phase: N/A
Study type: Interventional

The mixed methods pilot study aims to evaluate the acceptability, feasibility, and implementation challenges of the TARANG intervention in villages in rural/tribal Rajasthan to inform the study design and operational details for a larger cluster-randomized controlled trial.

NCT ID: NCT06300034 Completed - Acceptability Clinical Trials

Parental Perceptions and Acceptance of Silver Diamine Fluoride in Italy

SDF
Start date: September 1, 2020
Phase:
Study type: Observational [Patient Registry]

Parental perceptions on staining due to Silver Diamine Fluoride (SDF) could affect its implementation in pediatric dentistry. This study represents the second part of a wider project focused on SDF aesthetic acceptability among Italian parents.

NCT ID: NCT06163274 Recruiting - Safety Clinical Trials

Trial to Assess Acceptability and Safety of Two Placebo Intravaginal Rings

MATRIX-003
Start date: February 28, 2024
Phase: Early Phase 1
Study type: Interventional

This research study is being conducted to find out how easy, comfortable, and safe intravaginal rings are for women to use. The two rings used in this study do not dispense any medications, are the same size, but differ in their flexibility and hardness. This study will enroll approximately 100 HIV-negative persons, aged18-45 years, and assigned female sex at birth from sites in the United States, South Africa, and Zimbabwe. Participants will be randomly assigned to use (self-insert) Ring A for 4 weeks and then Ring B for 4 weeks or Ring B first followed by Ring A. There will be a 1-3-week rest period between using the two different rings. The study involves answering questions, undergoing pelvic examinations, and collecting blood and vaginal fluid samples over a total of 7 in-person visits and 2 telephone calls over approximately 9-11 weeks. In addition, both participants and approximately 30 of their sexual partners will be asked to take part in in-depth interviews to further assess acceptability, attitudes, and experiences with ring use to gauge interest in the future use of intravaginal rings as a HIV prevention option.

NCT ID: NCT06046053 Recruiting - Safety Clinical Trials

MATRIX-002: Trial to Assess Acceptability and Safety of Two Placebo Vaginal Films

Start date: October 18, 2023
Phase: Early Phase 1
Study type: Interventional

This study will enroll approximately 100 HIV-negative persons, aged18-45 years, and assigned female sex at birth from sites in the United States, Kenya, South Africa, and Zimbabwe. The study will assess the acceptability and safety of two placebo vaginal films. The placebo films do not contain any active medication, are the same size, but differ by shape (square versus rounded corners). Participants will be randomly assigned to one of the two films and asked to use (self-insert) the assigned film two times (approximately one month apart). Participants will be asked to refrain from sexual activity during the first month of use and may resume usual sexual activity during the second month of use. The study involves answering questions, undergoing pelvic examinations, and collecting blood and vaginal fluid samples. The study involves a total of 10 visits/contacts, including in person visits and telephone calls over approximately 9 weeks. In addition, both participants and approximately 30 of their sexual partners will be asked to take part in in depth interviews to further assess acceptability, attitudes, and experiences with film use to gauge interest in the future use of vaginal films as a HIV prevention option.

NCT ID: NCT05861076 Active, not recruiting - Side Effect Clinical Trials

Moringa Powder Acceptability Trial Among Healthy Adults

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

The study is a randomized acceptability trial involving the provision of three different doses of Moringa powder to be consumed daily by study participants.

NCT ID: NCT05139563 Active, not recruiting - Acceptability Clinical Trials

South African Male User Research on Acceptability of Implants and Injections

SAMURAI
Start date: July 12, 2022
Phase: N/A
Study type: Interventional

The overall aims of SAMURAI (South African Male User Research on Acceptability of Implants and Injections) are to assess acceptability of, and preferences for, novel long-acting pre-exposure prophylaxis (LA-PrEP) delivery formulation use among key end-users: heterosexual men and men-who-have-sex-with-men (MSM) in South Africa, a country most impacted by human immunodeficiency virus (HIV) incidence and prevalence. Early involvement of men in product development is an important opportunity to measure and address product acceptability and factors that may influence adherence and to foster male ownership of novel HIV prevention delivery modalities.

NCT ID: NCT04486677 Completed - Feasibility Clinical Trials

Caring Cards to and From Veterans: A Peer Approach to Suicide Prevention

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Veteran suicide is a national problem; social disconnection is an important contributor to suicide risk. This pilot study will recruit Veterans to take part in a peer-centered intervention called Caring Cards (CC). CC gives Veterans who have a history of increased suicide risk the opportunity to make cards that are then sent to Veterans who are currently at high-risk for suicide. This study will directly benefit Veterans and contribute to the quality of services provided by VA by creating a safe, creative space for Veterans with lived experience related to suicide risk to join together to provide messages of hope, community, and resilience to their peers at risk for suicide. Helping Veterans support one another provides a bridge for social connection, which may help prevent Veteran suicide. This intervention may also improve Veterans' satisfaction with VA healthcare and engagement with mental health treatment.

NCT ID: NCT04391036 Completed - Safety Clinical Trials

Randomized Cross-Over Study of Self-Insertion of Two Placebo Vaginal Film Formulations

FAME103B
Start date: July 14, 2020
Phase: N/A
Study type: Interventional

This is a double-blinded crossover study to evaluate whether Eudragit® content impacts the ability to self-insert placebo vaginal films. Thirty women will self-insert one high and and one low Eudragit® content film. The insertion order will be randomized in a 1:1 ratio. After inserting each film, participants will complete a survey reporting their perceptions and experience. The primary endpoint is successful insertion defined as all of the film inside the vagina upon visual assessment by a study clinician. Secondary outcomes include preference for the low level or high level Eudragit® formulation film with respect to insertion and participants' description of identified challenges.