Vestibular Abnormality — Effects of Infrasound Exposure on Measures of Endolymphatic Hydrops
Citation(s)
Adams ME, Heidenreich KD, Kileny PR Audiovestibular testing in patients with Meniere's disease. Otolaryngol Clin North Am. 2010 Oct;43(5):995-1009. doi: 10.1016/j.otc.2010.05.008. Review.
Berglund B, Hassmén P, Job RF Sources and effects of low-frequency noise. J Acoust Soc Am. 1996 May;99(5):2985-3002. Review.
Blakley BW, Wong V Normal Values for Cervical Vestibular-Evoked Myogenic Potentials. Otol Neurotol. 2015 Jul;36(6):1069-73. doi: 10.1097/MAO.0000000000000752.
Bonucci AS, Hyppolito MA Comparison of the use of tympanic and extratympanic electrodes for electrocochleography. Laryngoscope. 2009 Mar;119(3):563-6. doi: 10.1002/lary.20105.
Coats AC The summating potential and Meniere's disease. I. Summating potential amplitude in Meniere and non-Meniere ears. Arch Otolaryngol. 1981 Apr;107(4):199-208.
Densert B, Arlinger S, Sass K, Hergils L Reproducibility of the electric response components in clinical electrocochleography. Audiology. 1994 Sep-Oct;33(5):254-63.
Duck FA Medical and non-medical protection standards for ultrasound and infrasound. Prog Biophys Mol Biol. 2007 Jan-Apr;93(1-3):176-91. Epub 2006 Aug 4. Review.
Durrant JD, Dallos P Modification of DIF summating potential components by stimulus biasing. J Acoust Soc Am. 1974 Aug;56(2):562-70.
Flock A, Flock B Hydrops in the cochlea can be induced by sound as well as by static pressure. Hear Res. 2000 Dec;150(1-2):175-88.
Janky KL, Shepard N Vestibular evoked myogenic potential (VEMP) testing: normative threshold response curves and effects of age. J Am Acad Audiol. 2009 Sep;20(8):514-22.
Kageyama T, Yano T, Kuwano S, Sueoka S, Tachibana H Exposure-response relationship of wind turbine noise with self-reported symptoms of sleep and health problems: A nationwide socioacoustic survey in Japan. Noise Health. 2016 Mar-Apr;18(81):53-61. doi: 10.4103/1463-1741.178478.
Koerner TK, Zhang Y, Nelson PB, Wang B, Zou H Neural indices of phonemic discrimination and sentence-level speech intelligibility in quiet and noise: A mismatch negativity study. Hear Res. 2016 Sep;339:40-9. doi: 10.1016/j.heares.2016.06.001. Epub 2016 Jun 4.
Leventhall G What is infrasound? Prog Biophys Mol Biol. 2007 Jan-Apr;93(1-3):130-7. Epub 2006 Aug 4. Review.
May M, McMurtry RY Wind Turbines and Adverse Health Effects: A Second Opinion. J Occup Environ Med. 2015 Oct;57(10):e130-2. doi: 10.1097/JOM.0000000000000447.
Salt AN, Hullar TE Responses of the ear to low frequency sounds, infrasound and wind turbines. Hear Res. 2010 Sep 1;268(1-2):12-21. doi: 10.1016/j.heares.2010.06.007. Epub 2010 Jun 16. Review.
Salt AN, Lichtenhan JT, Gill RM, Hartsock JJ Large endolymphatic potentials from low-frequency and infrasonic tones in the guinea pig. J Acoust Soc Am. 2013 Mar;133(3):1561-71. doi: 10.1121/1.4789005.
Salt AN Acute endolymphatic hydrops generated by exposure of the ear to nontraumatic low-frequency tones. J Assoc Res Otolaryngol. 2004 Jun;5(2):203-14.
Schmidt JH, Klokker M Health effects related to wind turbine noise exposure: a systematic review. PLoS One. 2014 Dec 4;9(12):e114183. doi: 10.1371/journal.pone.0114183. eCollection 2014. Review.
Seo YJ, Kim J, Choi JY, Lee WS Visualization of endolymphatic hydrops and correlation with audio-vestibular functional testing in patients with definite Meniere's disease. Auris Nasus Larynx. 2013 Apr;40(2):167-72. doi: 10.1016/j.anl.2012.07.009. Epub 2012 Aug 4.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
