NCT05904795 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Andrade SE, Harrold LR, Tjia J, Cutrona SL, Saczynski JS, Dodd KS, Goldberg RJ, Gurwitz JH
A systematic review of validated methods for identifying cerebrovascular accident or transient ischemic attack using administrative data. Pharmacoepidemiol Drug Saf. 2012 Jan;21 Suppl 1(Suppl 1):100-28. doi: 10.1002/pds.2312.
Gillespie CD, Wigington C, Hong Y; Centers for Disease Control and Prevention (CDC)
Coronary heart disease and stroke deaths - United States, 2009. MMWR Suppl. 2013 Nov 22;62(3):157-60.
Harris JE, Eng JJ
Paretic upper-limb strength best explains arm activity in people with stroke. Phys Ther. 2007 Jan;87(1):88-97. doi: 10.2522/ptj.20060065. Epub 2006 Dec 19.
Hendricks HT, van Limbeek J, Geurts AC, Zwarts MJ
Motor recovery after stroke: a systematic review of the literature. Arch Phys Med Rehabil. 2002 Nov;83(11):1629-37. doi: 10.1053/apmr.2002.35473.
Mergenthaler P, Dirnagl U, Meisel A
Pathophysiology of stroke: lessons from animal models. Metab Brain Dis. 2004 Dec;19(3-4):151-67. doi: 10.1023/b:mebr.0000043966.46964.e6.
Pak S, Patten C
Strengthening to promote functional recovery poststroke: an evidence-based review. Top Stroke Rehabil. 2008 May-Jun;15(3):177-99. doi: 10.1310/tsr1503-177.
Zuber M, Mas JL
[Epidemiology of cerebrovascular accidents]. Rev Neurol (Paris). 1992;148(4):243-55. French.

Comparative Effects of Proprioceptive Neuromuscular Facilitation Strengthening Exercises and De-lorme and Watkins Exercises Program on Upper Limb Function and Strength in Chronic Stroke Patients

Details for clinical trial NCT05904795

Clinical trial NCT05904795 - References