NCT01951547 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Boutaga K, van Winkelhoff AJ, Vandenbroucke-Grauls CM, Savelkoul PH
Comparison of real-time PCR and culture for detection of Porphyromonas gingivalis in subgingival plaque samples. J Clin Microbiol. 2003 Nov;41(11):4950-4.
Boutaga K, van Winkelhoff AJ, Vandenbroucke-Grauls CM, Savelkoul PH
The additional value of real-time PCR in the quantitative detection of periodontal pathogens. J Clin Periodontol. 2006 Jun;33(6):427-33.
Taiyeb-Ali TB, Raman RP, Vaithilingam RD
Relationship between periodontal disease and diabetes mellitus: an Asian perspective. Periodontol 2000. 2011 Jun;56(1):258-68. doi: 10.1111/j.1600-0757.2010.00370.x.
Taylor GW, Borgnakke WS
Periodontal disease: associations with diabetes, glycemic control and complications. Oral Dis. 2008 Apr;14(3):191-203. doi: 10.1111/j.1601-0825.2008.01442.x. Review.
Taylor GW, Burt BA, Becker MP, Genco RJ, Shlossman M, Knowler WC, Pettitt DJ
Severe periodontitis and risk for poor glycemic control in patients with non-insulin-dependent diabetes mellitus. J Periodontol. 1996 Oct;67(10 Suppl):1085-93.

The Effect of Non-surgical Periodontal Therapy on Host Response and Microbiological Profile of Type 2 Diabetics With Periodontal Disease.

Clinical trial NCT01951547 - References