Tuberculosis — My Mobile Wallet: An Intervention for Tuberculosis Medication Adherence in Rural Uganda
Citation(s)
Adane AA, Alene KA, Koye DN, Zeleke BM Non-adherence to anti-tuberculosis treatment and determinant factors among patients with tuberculosis in northwest Ethiopia. PLoS One. 2013 Nov 11;8(11):e78791. doi: 10.1371/journal.pone.0078791. eCollection 2013.
Horsburgh CR Jr, Barry CE 3rd, Lange C Treatment of Tuberculosis. N Engl J Med. 2015 Nov 26;373(22):2149-60. doi: 10.1056/NEJMra1413919. No abstract available.
Linnemayr S, Glick P, Kityo C, Mugyeni P, Wagner G Prospective cohort study of the impact of antiretroviral therapy on employment outcomes among HIV clients in Uganda. AIDS Patient Care STDS. 2013 Dec;27(12):707-14. doi: 10.1089/apc.2013.0139.
Linnemayr S, Lawson BS, Glick P, Wagner G Economic Status and Coping Mechanisms of Individuals Seeking HIV Care in Uganda. J Afr Econ. 2011 Jun;20(3):505-529. doi: 10.1093/jae/ejr014. Epub 2011 May 4.
Linnemayr S, Stecher C Behavioral Economics Matters for HIV Research: The Impact of Behavioral Biases on Adherence to Antiretrovirals (ARVs). AIDS Behav. 2015 Nov;19(11):2069-75. doi: 10.1007/s10461-015-1076-0.
Linnemayr, S , Consumption smoothing and HIV/AIDS: The case of two communities in South Africa. Economic Development and Cultural Change, 2010. 58(3): p. 475-506.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
