Thumb Osteoarthritis — Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis
Citation(s)
Barthel L, Hidalgo Diaz JJ, Vernet P, Gouzou S, Facca S, Igeta Y, Liverneaux P Results of the treatment of first carpometacarpal joint osteoarthritis: trapeziectomy alone versus trapeziectomy associated with suspensionplasty. Eur J Orthop Surg Traumatol. 2018 Dec;28(8):1555-1561. doi: 10.1007/s00590-018-2173-3. Epub 2018 Mar 7.
Calfee RP, Adams AA Clinical research and patient-rated outcome measures in hand surgery. J Hand Surg Am. 2012 Apr;37(4):851-5. doi: 10.1016/j.jhsa.2012.01.043.
Dupont WD, Plummer WD Jr Power and sample size calculations. A review and computer program. Control Clin Trials. 1990 Apr;11(2):116-28.
Eaton RG, Littler JW Ligament reconstruction for the painful thumb carpometacarpal joint. J Bone Joint Surg Am. 1973 Dec;55(8):1655-66.
Gervis WH, Wells T A review of excision of the trapezium for osteoarthritis of the trapezio-metacarpal joint after twenty-five years. J Bone Joint Surg Br. 1973 Feb;55(1):56-7.
Heller GZ, Manuguerra M, Chow R How to analyze the Visual Analogue Scale: Myths, truths and clinical relevance. Scand J Pain. 2016 Oct;13:67-75. doi: 10.1016/j.sjpain.2016.06.012. Epub 2016 Jul 27. Review.
Kapandji A [Clinical test of apposition and counter-apposition of the thumb]. Ann Chir Main. 1986;5(1):67-73. French.
Kuhns CA, Emerson ET, Meals RA Hematoma and distraction arthroplasty for thumb basal joint osteoarthritis: a prospective, single-surgeon study including outcomes measures. J Hand Surg Am. 2003 May;28(3):381-9.
Martou G, Veltri K, Thoma A Surgical treatment of osteoarthritis of the carpometacarpal joint of the thumb: a systematic review. Plast Reconstr Surg. 2004 Aug;114(2):421-32. Review.
Nicholson RH, Crawley FP Revising the Declaration of Helsinki: a fresh start. Bull Med Ethics. 1999 Oct;No. 151:13-7.
Sodha S, Ring D, Zurakowski D, Jupiter JB Prevalence of osteoarthrosis of the trapeziometacarpal joint. J Bone Joint Surg Am. 2005 Dec;87(12):2614-2618. doi: 10.2106/JBJS.E.00104.
Vermeulen GM, Brink SM, Slijper H, Feitz R, Moojen TM, Hovius SE, Selles RW Trapeziometacarpal arthrodesis or trapeziectomy with ligament reconstruction in primary trapeziometacarpal osteoarthritis: a randomized controlled trial. J Bone Joint Surg Am. 2014 May 7;96(9):726-33. doi: 10.2106/JBJS.L.01344.
Wajon A, Vinycomb T, Carr E, Edmunds I, Ada L Surgery for thumb (trapeziometacarpal joint) osteoarthritis. Cochrane Database Syst Rev. 2015 Feb 23;(2):CD004631. doi: 10.1002/14651858.CD004631.pub4. Review. Update in: Cochrane Database Syst Rev. 2017 Apr 03;4:CD004631.
Distraction Versus Interposition Arthroplasty for Thumb Carpometacarpal Joint Osteoarthritis: A Randomized Controlled Trial
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.