NCT01225497 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Alfredson H, Pietilä T, Jonsson P, Lorentzon R
Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med. 1998 May-Jun;26(3):360-6.
Ohberg L, Lorentzon R, Alfredson H
Eccentric training in patients with chronic Achilles tendinosis: normalised tendon structure and decreased thickness at follow up. Br J Sports Med. 2004 Feb;38(1):8-11; discussion 11.
Rompe JD, Furia JP, Maffulli N
Mid-portion Achilles tendinopathy--current options for treatment. Disabil Rehabil. 2008;30(20-22):1666-76. doi: 10.1080/09638280701785825. Review.
Roos EM, Engström M, Lagerquist A, Söderberg B
Clinical improvement after 6 weeks of eccentric exercise in patients with mid-portion Achilles tendinopathy -- a randomized trial with 1-year follow-up. Scand J Med Sci Sports. 2004 Oct;14(5):286-95.

Effects of Two Eccentric Exercise Protocols on Reported Pain Intensity, Function, and Treatment Satisfaction in Adults With Chronic Mid-portion Achilles Tendinopathies

Details for clinical trial NCT01225497

Clinical trial NCT01225497 - References