NCT03107546 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Crowe JM, Simpson K, Johnson W, Allen J
Reliability of photographic analysis in determining change in scar appearance. J Burn Care Rehabil. 1998 Mar-Apr;19(2):183-6. doi: 10.1097/00004630-199803000-00019.
Dao KD, Wood VE, Billings A
Treatment of syndactyly. Tech Hand Up Extrem Surg. 1998 Sep;2(3):166-77. doi: 10.1097/00130911-199809000-00004. No abstract available.
Draaijers LJ, Tempelman FR, Botman YA, Tuinebreijer WE, Middelkoop E, Kreis RW, van Zuijlen PP
The patient and observer scar assessment scale: a reliable and feasible tool for scar evaluation. Plast Reconstr Surg. 2004 Jun;113(7):1960-5; discussion 1966-7. doi: 10.1097/01.prs.0000122207.28773.56.
Landi A, Garagnani L, Leti Acciaro A, Lando M, Ozben H, Gagliano MC
Hyaluronic acid scaffold for skin defects in congenital syndactyly release surgery: a novel technique based on the regenerative model. J Hand Surg Eur Vol. 2014 Nov;39(9):994-1000. doi: 10.1177/1753193414529046. Epub 2014 Mar 24.
Perna RB, Loughan AR, Le JA, Hertza J
Prenatal and perinatal anesthesia and the long-term cognitive sequelae: a review. Appl Neuropsychol Child. 2015;4(1):65-71. doi: 10.1080/21622965.2013.779275. Epub 2013 Oct 24.
Withey SJ, Kangesu T, Carver N, Sommerlad BC
The open finger technique for the release of syndactyly. J Hand Surg Br. 2001 Feb;26(1):4-7. doi: 10.1054/jhsb.2000.0575.

Comparison of Scar Formation in Syndactyly Release Surgery With Full Thickness Skin Graft Versus Skin Graft Substitute

Clinical trial NCT03107546 - References