Surgery — Comparison Between Laryngoscope McCoy With Macintosh
Citation(s)
Bilgin H, Bozkurt M Tracheal intubation using the ILMA, C-Trach or McCoy laryngoscope in patients with simulated cervical spine injury. Anaesthesia. 2006 Jul;61(7):685-91.
Noppens RR, Geimer S, Eisel N, David M, Piepho T Endotracheal intubation using the C-MAC® video laryngoscope or the Macintosh laryngoscope: a prospective, comparative study in the ICU. Crit Care. 2012 Jun 13;16(3):R103. doi: 10.1186/cc11384.
Randell T Haemodynamic responses to intubation: what more do we have to know? Acta Anaesthesiol Scand. 2004 Apr;48(4):393-5.
Xue FS, Wang Q, Liao X, Yuan YJ Cardiovascular intubation responses with Airway Scope and Macintosh laryngoscope. Anaesthesia. 2012 Apr;67(4):434-5; author reply 435-6. doi: 10.1111/j.1365-2044.2012.07071_1.x.
Comparison of Cardiovascular Response and Ease of Intubation Using Laryngoscope McCoy With Macintosh in Malay Race in Indonesia
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
