NCT02879279 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Kwakkel G, Kollen BJ, Krebs HI
Effects of robot-assisted therapy on upper limb recovery after stroke: a systematic review. Neurorehabil Neural Repair. 2008 Mar-Apr;22(2):111-21. Epub 2007 Sep 17. Review.
Mehrholz J, Pohl M, Platz T, Kugler J, Elsner B
Electromechanical and robot-assisted arm training for improving activities of daily living, arm function, and arm muscle strength after stroke. Cochrane Database Syst Rev. 2015 Nov 7;(11):CD006876. doi: 10.1002/14651858.CD006876.pub4. Review. Update in: Cochrane Database Syst Rev. 2018 Sep 03;9:CD006876.
Norouzi-Gheidari N, Archambault PS, Fung J
Effects of robot-assisted therapy on stroke rehabilitation in upper limbs: systematic review and meta-analysis of the literature. J Rehabil Res Dev. 2012;49(4):479-96. Review.
Pollock A, Farmer SE, Brady MC, Langhorne P, Mead GE, Mehrholz J, van Wijck F
Interventions for improving upper limb function after stroke. Cochrane Database Syst Rev. 2014 Nov 12;(11):CD010820. doi: 10.1002/14651858.CD010820.pub2. Review.

Efficacy of a Multi-segmental Robotic and Technological Upper Limb Rehabilitation Program, Compared With Traditional Therapy, in Individuals With Acute and Sub-acute Stroke: a Multicenter, Randomized, Controlled Clinical Trial.

Details for clinical trial NCT02879279

Clinical trial NCT02879279 - References