Barker WH, Mullooly JP Stroke in a defined elderly population, 1967-1985. A less lethal and disabling but no less common disease. Stroke. 1997 Feb;28(2):284-90. Review.
Janssen AM, Oostendorp TF, Stegeman DF The coil orientation dependency of the electric field induced by TMS for M1 and other brain areas. J Neuroeng Rehabil. 2015 May 17;12:47. doi: 10.1186/s12984-015-0036-2.
Pambakian AL, Kennard C Can visual function be restored in patients with homonymous hemianopia? Br J Ophthalmol. 1997 Apr;81(4):324-8. Review.
Perez C, Chokron S Rehabilitation of homonymous hemianopia: insight into blindsight. Front Integr Neurosci. 2014 Oct 22;8:82. doi: 10.3389/fnint.2014.00082. eCollection 2014. Review.
Sabel BA, Henrich-Noack P, Fedorov A, Gall C Vision restoration after brain and retina damage: the "residual vision activation theory". Prog Brain Res. 2011;192:199-262. doi: 10.1016/B978-0-444-53355-5.00013-0. Review.
Urbanski M, Coubard OA, Bourlon C Visualizing the blind brain: brain imaging of visual field defects from early recovery to rehabilitation techniques. Front Integr Neurosci. 2014 Sep 30;8:74. doi: 10.3389/fnint.2014.00074. eCollection 2014. Review.
The Efficacy of Navigated Perilesional Repetitive Transcranial Magnetic Stimulation on Post-Stroke Visual Field Defects
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
