Spinal Cord Injuries — Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.
Citation(s)
Arsh A, Darain H, Haq ZU, Zeb A, Ali I, Ilyas SM Epidemiology of spinal cord injuries due to bomb blast attacks, managed at paraplegic centre peshawar, pakistan: a nine years retrospective study. KMUJ: KHYBER MEDICAL UNIVERSITY JOURNAL. 2017;9(2).
DeVeau KM, Harman KA, Squair JW, Krassioukov AV, Magnuson DSK, West CR A comparison of passive hindlimb cycling and active upper-limb exercise provides new insights into systolic dysfunction after spinal cord injury. Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H861-H870. doi: 10.1152/ajpheart.00046.2017. Epub 2017 Jul 14.
Devillard X, Rimaud D, Roche F, Calmels P Effects of training programs for spinal cord injury. Ann Readapt Med Phys. 2007 Jul;50(6):490-8, 480-9. Epub 2007 Apr 24. Review. English, French.
Kloosterman MG, Snoek GJ, Jannink MJ Systematic review of the effects of exercise therapy on the upper extremity of patients with spinal-cord injury. Spinal Cord. 2009 Mar;47(3):196-203. doi: 10.1038/sc.2008.113. Epub 2008 Sep 30. Review.
Postma K, Bussmann JB, Haisma JA, van der Woude LH, Bergen MP, Stam HJ Predicting respiratory infection one year after inpatient rehabilitation with pulmonary function measured at discharge in persons with spinal cord injury. J Rehabil Med. 2009 Sep;41(9):729-33. doi: 10.2340/16501977-0410.
Postma K, Haisma JA, de Groot S, Hopman MT, Bergen MP, Stam HJ, Bussmann JB Changes in pulmonary function during the early years after inpatient rehabilitation in persons with spinal cord injury: a prospective cohort study. Arch Phys Med Rehabil. 2013 Aug;94(8):1540-6. doi: 10.1016/j.apmr.2013.02.006. Epub 2013 Feb 14.
Terson de Paleville D, Lorenz D Compensatory muscle activation during forced respiratory tasks in individuals with chronic spinal cord injury. Respir Physiol Neurobiol. 2015 Oct;217:54-62. doi: 10.1016/j.resp.2015.07.001. Epub 2015 Jul 11.
Tørhaug T, Brurok B, Hoff J, Helgerud J, Leivseth G Arm Cycling Combined with Passive Leg Cycling Enhances VO(2peak) in Persons with Spinal Cord Injury Above the Sixth Thoracic Vertebra. Top Spinal Cord Inj Rehabil. 2018 Winter;24(1):86-95. doi: 10.1310/sci17-00029. Epub 2017 Nov 20.
West CR, Currie KD, Gee C, Krassioukov AV, Borisoff J Active-Arm Passive-Leg Exercise Improves Cardiovascular Function in Spinal Cord Injury. Am J Phys Med Rehabil. 2015 Nov;94(11):e102-6. doi: 10.1097/PHM.0000000000000358.
Zhan S, Cerny FJ, Gibbons WJ, Mador MJ, Wu YW Development of an unsupported arm exercise test in patients with chronic obstructive pulmonary disease. J Cardiopulm Rehabil. 2006 May-Jun;26(3):180-7; discussion 188-90.
Effects of Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
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