Janssen KC, Phillipson S, O'Connor J, Johns MW Validation of the Epworth Sleepiness Scale for Children and Adolescents using Rasch analysis. Sleep Med. 2017 May;33:30-35. doi: 10.1016/j.sleep.2017.01.014. Epub 2017 Feb 12.
Kanady JC, Drummond SP, Mednick SC Actigraphic assessment of a polysomnographic-recorded nap: a validation study. J Sleep Res. 2011 Mar;20(1 Pt 2):214-22. doi: 10.1111/j.1365-2869.2010.00858.x.
Lee YJ, Park J, Kim S, Cho SJ, Kim SJ Academic performance among adolescents with behaviorally induced insufficient sleep syndrome. J Clin Sleep Med. 2015 Jan 15;11(1):61-8. doi: 10.5664/jcsm.4368.
Mah CD, Mah KE, Kezirian EJ, Dement WC The effects of sleep extension on the athletic performance of collegiate basketball players. Sleep. 2011 Jul 1;34(7):943-50. doi: 10.5665/SLEEP.1132.
Natale V, Plazzi G, Martoni M Actigraphy in the assessment of insomnia: a quantitative approach. Sleep. 2009 Jun;32(6):767-71.
National Sleep Foundation Eight major obstacles to delaying school start times. http://sleepfoundation.org/sleep-news/eight-major-obstacles-delaying-school-start-times.
Schwartz J, Simon RD Jr Sleep extension improves serving accuracy: A study with college varsity tennis players. Physiol Behav. 2015 Nov 1;151:541-4. doi: 10.1016/j.physbeh.2015.08.035. Epub 2015 Sep 1.
Wolfson AR, Carskadon MA Sleep schedules and daytime functioning in adolescents. Child Dev. 1998 Aug;69(4):875-87.
The Effect of Sleep Extension in Teenage Girls at a College Preparatory High School
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
