NCT06260280 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Baumann Q, Bulaid Y, Van Vliet A, Gabrion A, Klein C, Mertl P
Sleep Deprivation Adversely Impacts Resident Performance for Simulated Arthroscopy. Arthrosc Sports Med Rehabil. 2021 Jul 9;3(4):e1125-e1132. doi: 10.1016/j.asmr.2021.04.001. eCollection 2021
Craven J, McCartney D, Desbrow B, Sabapathy S, Bellinger P, Roberts L, Irwin C
Effects of Acute Sleep Loss on Physical Performance: A Systematic and Meta-Analytical Review. Sports Med. 2022 Nov;52(11):2669-2690. doi: 10.1007/s40279-022-01706-y. Epub 2022
Dai XJ, Jiang J, Zhang Z, Nie X, Liu BX, Pei L, Gong H, Hu J, Lu G, Zhan Y
Plasticity and Susceptibility of Brain Morphometry Alterations to Insufficient Sleep. Front Psychiatry. 2018 Jun 27;9:266. doi: 10.3389/fpsyt.2018.00266. eCollection 2018.
Elvsashagen T, Zak N, Norbom LB, Pedersen PO, Quraishi SH, Bjornerud A, Alnaes D, Doan NT, Malt UF, Groote IR, Westlye LT
Evidence for cortical structural plasticity in humans after a day of waking and sleep deprivation. Neuroimage. 2017 Aug 1;156:214-22
Mason GM, Lokhandwala S, Riggins T, Spencer RMC
Sleep and human cognitive development. Sleep Med Rev. 2021 Jun;57:101472. doi: 10.1016/j.smrv.2021.101472. Epub 2021 Mar 13.
Perotta B, Arantes-Costa FM, Enns SC, Figueiro-Filho EA, Paro H, Santos IS, Lorenzi-Filho G, Martins MA, Tempski PZ
Sleepiness, sleep deprivation, quality of life, mental symptoms and perception of academic environment in medical students. BMC Med Educ.

Relationship Between Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume Assessed by Nuclear Magnetic Resonance in First-Year Medical Residents

Details for clinical trial NCT06260280

Clinical trial NCT06260280 - References