NCT03970707 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Ade JD, Harley JA, Bradley PS
Physiological response, time-motion characteristics, and reproducibility of various speed-endurance drills in elite youth soccer players: small-sided games versus generic running. Int J Sports Physiol Perform. 2014 May;9(3):471-9. doi: 10.1123/ijspp.2013-0390. Epub 2014 Feb 7.
Fatouros IG, Chatzinikolaou A, Douroudos II, Nikolaidis MG, Kyparos A, Margonis K, Michailidis Y, Vantarakis A, Taxildaris K, Katrabasas I, Mandalidis D, Kouretas D, Jamurtas AZ
Time-course of changes in oxidative stress and antioxidant status responses following a soccer game. J Strength Cond Res. 2010 Dec;24(12):3278-86. doi: 10.1519/JSC.0b013e3181b60444.
Hill-Haas SV, Dawson B, Impellizzeri FM, Coutts AJ
Physiology of small-sided games training in football: a systematic review. Sports Med. 2011 Mar 1;41(3):199-220. doi: 10.2165/11539740-000000000-00000. Review.
Mohr M, Krustrup P, Bangsbo J
Match performance of high-standard soccer players with special reference to development of fatigue. J Sports Sci. 2003 Jul;21(7):519-28.
Owen AL, Wong DP, Paul D, Dellal A
Physical and technical comparisons between various-sided games within professional soccer. Int J Sports Med. 2014 Apr;35(4):286-92. doi: 10.1055/s-0033-1351333. Epub 2013 Sep 10.

Investigation on Recovery Kinetics After the Use of Small Sided Games With a Small and Large Number of Players and Large Pitch Area

Clinical trial NCT03970707 - References