Clinical trial NCT03334006 - References

Sepsis — Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis (PEPPER Trial).

Citation(s)

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  Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med. 2001 Aug 1;164(3):396-402. doi: 10.1164/ajrccm.164.3.2009052.
•   Heyland DK, Muscedere J, Drover J, Jiang X, Day AG; Canadian Critical Care Trials Group
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•   Janssens U
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•   Koo DJ, Zhou M, Chaudry IH, Wang P
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•   Kujath P
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•   Marino R, Struck J, Maisel AS, Magrini L, Bergmann A, Di Somma S
  Plasma adrenomedullin is associated with short-term mortality and vasopressor requirement in patients admitted with sepsis. Crit Care. 2014 Feb 17;18(1):R34. doi: 10.1186/cc13731.
•   Maruna P, Nedelnikova K, Gurlich R
  Physiology and genetics of procalcitonin. Physiol Res. 2000;49 Suppl 1:S57-61.
•   Mebazaa A, Laterre PF, Russell JA, Bergmann A, Gattinoni L, Gayat E, Harhay MO, Hartmann O, Hein F, Kjolbye AL, Legrand M, Lewis RJ, Marshall JC, Marx G, Radermacher P, Schroedter M, Scigalla P, Stough WG, Struck J, Van den Berghe G, Yilmaz MB, Angus DC
  Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure. J Intensive Care. 2016 Mar 31;4:24. doi: 10.1186/s40560-016-0151-6. eCollection 2016.
•   Meisel C, Schefold JC, Pschowski R, Baumann T, Hetzger K, Gregor J, Weber-Carstens S, Hasper D, Keh D, Zuckermann H, Reinke P, Volk HD
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•   Monneret G, Doche C, Durand DV, Lepape A, Bienvenu J
  Procalcitonin as a specific marker of bacterial infection in adults. Clin Chem Lab Med. 1998 Jan;36(1):67-8. doi: 10.1515/CCLM.1998.012. No abstract available.
•   Muller B, Becker KL, Schachinger H, Rickenbacher PR, Huber PR, Zimmerli W, Ritz R
  Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med. 2000 Apr;28(4):977-83. doi: 10.1097/00003246-200004000-00011.
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  Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med. 2004 Nov;32(11):2173-82. doi: 10.1097/01.ccm.0000145229.59014.6c.
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  Effects of high-dose of intravenous immunoglobulin and antibiotics on survival for severe sepsis undergoing surgery. Shock. 2005 Apr;23(4):298-304. doi: 10.1097/01.shk.0000157302.69125.f8.
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  A single nucleotide polymorphism in NF-kappaB inducing kinase is associated with mortality in septic shock. J Immunol. 2011 Feb 15;186(4):2321-8. doi: 10.4049/jimmunol.1002864. Epub 2011 Jan 21.
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•   Van Snick J
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•   Zhu Y, Qiu HB, Liu JT, Wang Y, Lin HY, Xu Y, Jiang L, Shi Y, Zhu X, Ning B, Cheng R, Xie ZY, Ma PL
  [Effect of endothelial nitric oxide synthase gene polymorphisms upon disease severity and outcome in septic patients]. Zhonghua Yi Xue Za Zhi. 2010 Apr 6;90(13):906-11. Chinese.

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis (PEPPER Trial).

Details for clinical trial NCT03334006