Rheumatoid Arthritis — A Physiotherapist Led Intervention to Promote Physical Activity in Rheumatoid Arthritis - a Pilot Study
Citation(s)
Brodin N, Hurkmans E, DiMatteo L, Nava T, Vliet Vlieland T, Opava CH Promotion of health-enhancing physical activity in rheumatoid arthritis: a comparative study on healthcare providers in Italy, The Netherlands and Sweden. Rheumatol Int. 2015 Oct;35(10):1665-73. doi: 10.1007/s00296-015-3267-4. Epub 2015 Apr 14.
Knittle K, De Gucht V, Hurkmans E, Peeters A, Ronday K, Maes S, Vlieland TV Targeting motivation and self-regulation to increase physical activity among patients with rheumatoid arthritis: a randomised controlled trial. Clin Rheumatol. 2015 Feb;34(2):231-8. doi: 10.1007/s10067-013-2425-x. Epub 2013 Nov 9.
Larkin L, Gallagher S, Cramp F, Brand C, Fraser A, Kennedy N Behaviour change interventions to promote physical activity in rheumatoid arthritis: a systematic review. Rheumatol Int. 2015 Oct;35(10):1631-40. doi: 10.1007/s00296-015-3292-3. Epub 2015 May 21. Review.
Larkin L, Gallagher S, Fraser A, Kennedy N If a joint is hot it's not the time: health professionals' views on developing an intervention to promote physical activity in rheumatoid arthritis. Disabil Rehabil. 2017 Jun;39(11):1106-1113. doi: 10.1080/09638288.2016.1180548. Epub 2016 Jun 8.
Larkin L, Kennedy N, Fraser A, Gallagher S 'It might hurt, but still it's good': People with rheumatoid arthritis beliefs and expectations about physical activity interventions. J Health Psychol. 2017 Nov;22(13):1678-1690. doi: 10.1177/1359105316633286. Epub 2016 Mar 8.
Larkin L, Nordgren B, Purtill H, Brand C, Fraser A, Kennedy N Criterion Validity of the activPAL Activity Monitor for Sedentary and Physical Activity Patterns in People Who Have Rheumatoid Arthritis. Phys Ther. 2016 Jul;96(7):1093-101. doi: 10.2522/ptj.20150281. Epub 2015 Dec 4.
Michie S, van Stralen MM, West R The behaviour change wheel: a new method for characterising and designing behaviour change interventions. Implement Sci. 2011 Apr 23;6:42. doi: 10.1186/1748-5908-6-42. Review.
Power D, Codd M, Ivers L, Sant S, Barry M Prevalence of rheumatoid arthritis in Dublin, Ireland: a population based survey. Ir J Med Sci. 1999 Jul-Sep;168(3):197-200.
Swärdh E, Brodin N Effects of aerobic and muscle strengthening exercise in adults with rheumatoid arthritis: a narrative review summarising a chapter in Physical activity in the prevention and treatment of disease (FYSS 2016). Br J Sports Med. 2016 Mar;50(6):362-7. doi: 10.1136/bjsports-2015-095793. Epub 2016 Feb 3. Review.
Tierney M, Fraser A, Kennedy N Physical activity in rheumatoid arthritis: a systematic review. J Phys Act Health. 2012 Sep;9(7):1036-48. Review.
A Physiotherapist Led Intervention to Promote Physical Activity in Rheumatoid Arthritis - a Pilot Study
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
