NCT02075424 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Hellhammer DH, Wüst S, Kudielka BM
Salivary cortisol as a biomarker in stress research. Psychoneuroendocrinology. 2009 Feb;34(2):163-71. doi: 10.1016/j.psyneuen.2008.10.026. Epub 2008 Dec 18. Review.
Kirschbaum C, Hellhammer DH
Salivary cortisol in psychobiological research: an overview. Neuropsychobiology. 1989;22(3):150-69. Review.
Kirschbaum C, Hellhammer DH
Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology. 1994;19(4):313-33. Review.
Nakajima Y, Takahashi T, Shetty V, Yamaguchi M
Patterns of salivary cortisol levels can manifest work stress in emergency care providers. J Physiol Sci. 2012 May;62(3):191-7. doi: 10.1007/s12576-012-0197-8. Epub 2012 Feb 19.
Weibel L, Gabrion I, Aussedat M, Kreutz G
Work-related stress in an emergency medical dispatch center. Ann Emerg Med. 2003 Apr;41(4):500-6.

Descriptive Study of Biological Stress and Perceived Stress in Call Regulation Operators and Doctors When Processing a Call at the Center 15

Clinical trial NCT02075424 - References