Bartlett JD, Close GL, MacLaren DP, Gregson W, Drust B, Morton JP High-intensity interval running is perceived to be more enjoyable than moderate-intensity continuous exercise: implications for exercise adherence. J Sports Sci. 2011 Mar;29(6):547-53. doi: 10.1080/02640414.2010.545427.
Boereboom CL, Phillips BE, Williams JP, Lund JN A 31-day time to surgery compliant exercise training programme improves aerobic health in the elderly. Tech Coloproctol. 2016 Jun;20(6):375-382. doi: 10.1007/s10151-016-1455-1. Epub 2016 Mar 25.
Buchheit M, Laursen PB High-intensity interval training, solutions to the programming puzzle. Part II: anaerobic energy, neuromuscular load and practical applications. Sports Med. 2013 Oct;43(10):927-54. doi: 10.1007/s40279-013-0066-5. Review.
Després JP Physical Activity, Sedentary Behaviours, and Cardiovascular Health: When Will Cardiorespiratory Fitness Become a Vital Sign? Can J Cardiol. 2016 Apr;32(4):505-13. doi: 10.1016/j.cjca.2015.12.006. Epub 2015 Dec 15. Review.
Devin JL, Sax AT, Hughes GI, Jenkins DG, Aitken JF, Chambers SK, Dunn JC, Bolam KA, Skinner TL The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial. J Cancer Surviv. 2016 Jun;10(3):467-79. doi: 10.1007/s11764-015-0490-7. Epub 2015 Oct 19.
Gibala MJ, Little JP, Macdonald MJ, Hawley JA Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol. 2012 Mar 1;590(5):1077-84. doi: 10.1113/jphysiol.2011.224725. Epub 2012 Jan 30. Review.
Gillen JB, Gibala MJ Is high-intensity interval training a time-efficient exercise strategy to improve health and fitness? Appl Physiol Nutr Metab. 2014 Mar;39(3):409-12. doi: 10.1139/apnm-2013-0187. Epub 2013 Sep 27.
Hamer M, Stamatakis E, Saxton JM The impact of physical activity on all-cause mortality in men and women after a cancer diagnosis. Cancer Causes Control. 2009 Mar;20(2):225-31. doi: 10.1007/s10552-008-9237-3. Epub 2008 Oct 2.
Mann T, Lamberts RP, Lambert MI Methods of prescribing relative exercise intensity: physiological and practical considerations. Sports Med. 2013 Jul;43(7):613-25. doi: 10.1007/s40279-013-0045-x. Review.
Martin E, Battaglini C, Hands B, Naumann FL Higher-intensity exercise helps cancer survivors remain motivated. J Cancer Surviv. 2016 Jun;10(3):524-33. doi: 10.1007/s11764-015-0498-z. Epub 2015 Nov 19.
Martin EA, Battaglini CL, Hands B, Naumann F Higher-Intensity Exercise Results in More Sustainable Improvements for VO2peak for Breast and Prostate Cancer Survivors. Oncol Nurs Forum. 2015 May;42(3):241-9. doi: 10.1188/15.ONF.42-03AP.
Metcalfe RS, Babraj JA, Fawkner SG, Vollaard NB Towards the minimal amount of exercise for improving metabolic health: beneficial effects of reduced-exertion high-intensity interval training. Eur J Appl Physiol. 2012 Jul;112(7):2767-75. doi: 10.1007/s00421-011-2254-z. Epub 2011 Nov 29.
Toohey K, Pumpa KL, Arnolda L, Cooke J, Yip D, Craft PS, Semple S A pilot study examining the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular risk factors in cancer survivors. PeerJ. 2016 Oct 20;4:e2613. eCollection 2016.
Ware, J E., Snow, K.K., Kosinski, M., Gandek, B. SF-36® Health Survey Manual and Interpretation Guide. Boston, MA: New England Medical Center, The Health Institute, 1993
Weston M, Taylor KL, Batterham AM, Hopkins WG Effects of low-volume high-intensity interval training (HIT) on fitness in adults: a meta-analysis of controlled and non-controlled trials. Sports Med. 2014 Jul;44(7):1005-17. doi: 10.1007/s40279-014-0180-z. Review.
World Health Organisation, 2010 Global Recommendations on Physical Activity for Health. [Online] Available from: http://apps.who.int/iris/bitstream/10665/44399/1/9789241599979_eng.pdf [Accessed: 11/04/2017]
Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients With Prostate Cancer
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.