Card JJ, Kuhn T, Solomon J, Benner TA, Wingood GM, DiClemente RJ Translating an effective group-based HIV prevention program to a program delivered primarily by a computer: methods and outcomes. AIDS Educ Prev. 2011 Apr;23(2):159-74. doi: 10.1521/aeap.2011.23.2.159.
Finer LB, Henshaw SK Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspect Sex Reprod Health. 2006 Jun;38(2):90-6.
Foundation, T A.E.C., Kids Count 2008 data book 2008, The Annie E. Casey Foundation Baltimore.
Frost JJ, Darroch JE Factors associated with contraceptive choice and inconsistent method use, United States, 2004. Perspect Sex Reprod Health. 2008 Jun;40(2):94-104. doi: 10.1363/4009408.
Fuller C, Clark RA, Kissinger P, Abdalian SE Clinical manifestations of infection with human immunodeficiency virus among adolescents in Louisiana. J Adolesc Health. 1996 Jun;18(6):422-8.
Guttmacher Institute, U S. Teenage Pregnancy Statistics: National and State Trends and Trends by Race and Ethnicity. . 2006, Guttmacher Institute: New York.
Hoffman, S D., By the numbers: The public costs of adolescent childbearing. 2006, The National Campaign to Prevent Teen Pregnancy.: Washington, DC.
Kissinger P, Clark R, Dumestre J, Bessinger R Incidence of three sexually transmitted diseases during a safer sex promotion program for HIV-infected women. J Gen Intern Med. 1996 Dec;11(12):750-2.
Kissinger, P , et al. Recurrent Trichomonas vaginalis among HIV positive and negative women. in 16th ISSTDR. 2005. Amsterdam, Netherlands.
Kost, K , Henshaw, S., & Carlin, L. , U.S. Teenage Pregnancies, Births and Abortions: National and State Trends and Trends by Race and Ethnicity. . 2010, Guttmacher: New York.
Wingood GM, DiClemente RJ The ADAPT-ITT model: a novel method of adapting evidence-based HIV Interventions. J Acquir Immune Defic Syndr. 2008 Mar 1;47 Suppl 1:S40-6. doi: 10.1097/QAI.0b013e3181605df1.
Yoo S, Johnson CC, Rice J, Manuel P A qualitative evaluation of the Students of Service (SOS) program for sexual abstinence in Louisiana. J Sch Health. 2004 Oct;74(8):329-34.
Zill, N , & O'Donnell, K., Child poverty rates by maternal risk factors: An update. 2004, WESTAT.
e-SiHLE: An Internet Pregnancy Prevention for Older Teenage Girls
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
