Clinical trial NCT05869344 - References

PreDiabetes — Black Bean (Phaseolus Vulgaris L.) Protein Hydrolysates Reduce Acute Postprandial Glucose Levels

Citation(s)

•   American Diabetes Association
  6. Glycemic Targets: Standards of Medical Care in Diabetes-2018. Diabetes Care. 2018 Jan;41(Suppl 1):S55-S64. doi: 10.2337/dc18-S006.
•   Luna-Vital DA, Mojica L, Gonza´lez de Meji´a E, Mendoza S, Loarca-Pin~a G
  Biological potential of protein hydrolysates and peptides from common bean (Phaseolus vulgaris L.): A review. Food Res Int [Internet]. 2015;76(P1):39- 50.
•   Mojica L, Chen K, de Mejia EG
  Impact of commercial precooking of common bean (Phaseolus vulgaris) on the generation of peptides, after pepsin-pancreatin hydrolysis, capable to inhibit dipeptidyl peptidase-IV. J Food Sci. 2015 Jan;80(1):H188-98. doi: 10.1111/1750-3841.12726. Epub 2014 Dec 11.
•   Mojica L, de Mejia EG
  Optimization of enzymatic production of anti-diabetic peptides from black bean (Phaseolus vulgaris L.) proteins, their characterization and biological potential. Food Funct. 2016 Feb;7(2):713-27. doi: 10.1039/c5fo01204j.
•   Mojica L, Gonzalez de Mejia E, Granados-Silvestre MA´, Menjivar M
  Evaluation of the hypoglycemic potential of a black bean hydrolyzed protein isolate and its pure peptides using in silico, in vitro and in vivo approaches. J Funct Foods. 2017B;31:274-86.
•   Mojica L, Luna-Vital DA, Gonzalez de Mejia E
  Black bean peptides inhibit glucose uptake in Caco-2 adenocarcinoma cells by blocking the expression and translocation pathway of glucose transporters. Toxicol Rep. 2018 Apr 27;5:552-560. doi: 10.1016/j.toxrep.2018.04.007. eCollection 2018.
•   Oseguera-Toledo ME, Gonzalez de Mejia E, Amaya-Llano SL
  Hard-to-cook bean (Phaseolus vulgaris L.) proteins hydrolyzed by alcalase and bromelain produced bioactive peptide fractions that inhibit targets of type-2 diabetes and oxidative stress. Food Res Int. 2015 Oct;76(Pt 3):839-851. doi: 10.1016/j.foodres.2015.07.046. Epub 2015 Aug 1.
•   Udenigwe, C
  C., Abioye, R. O., Okagu, I. U., & Obeme-Nmom, J. I. (2021). Bioaccessibility of bioactive peptides: Recent advances and perspectives. Current Opinion in Food Science, 39, 182-189.
•   Valencia-Mejia E, Batista KA, Fernandez JJA, Fernandes KF
  Antihyperglycemic and hypoglycemic activity of naturally occurring peptides and protein hydrolysates from easy-to-cook and hard-to-cook beans (Phaseolus vulgaris L.). Food Res Int. 2019 Jul;121:238-246. doi: 10.1016/j.foodres.2019.03.043. Epub 2019 Mar 20.

Black Bean (Phaseolus Vulgaris L.) Protein Hydrolysates Reduce Acute Postprandial Glucose Levels in Prediabetes and Normal Glucose Tolerance Adults

Details for clinical trial NCT05869344