Clinical trial NCT00158743 - References

Pre-eclampsia — Efficacy Study of Digibind for Treatment of Severe Preeclampsia

Citation(s)

•   Adair CD, Buckalew V, Taylor K, Ernest JM, Frye AH, Evans C, Veille JC
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•   Graves SW, Williams GH
  An endogenous ouabain-like factor associated with hypertensive pregnant women. J Clin Endocrinol Metab. 1984 Dec;59(6):1070-4.
•   Gruber KA, Whitaker JM, Buckalew VM Jr
  Endogenous digitalis-like substance in plasma of volume-expanded dogs. Nature. 1980 Oct 23;287(5784):743-5.
•   Gusdon JP Jr, Buckalew VM Jr, Hennessy JF
  A digoxin-like immunoreactive substance in preeclampsia. Am J Obstet Gynecol. 1984 Sep 1;150(1):83-5.
•   Krep H, Price DA, Soszynski P, Tao QF, Graves SW, Hollenberg NK
  Volume sensitive hypertension and the digoxin-like factor. Reversal by a Fab directed against digoxin in DOCA-salt hypertensive rats. Am J Hypertens. 1995 Sep;8(9):921-7.
•   Krep HH, Graves SW, Price DA, Lazarus M, Ensign A, Soszynski PA, Hollenberg NK
  Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications. Am J Hypertens. 1996 Jan;9(1):39-46.
•   Lopatin DA, Ailamazian EK, Dmitrieva RI, Shpen VM, Fedorova OV, Doris PA, Bagrov AY
  Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia. J Hypertens. 1999 Aug;17(8):1179-87.
•   Poston L, Morris JF, Wolfe CD, Hilton PJ
  Serum digoxin-like substances in pregnancy-induced hypertension. Clin Sci (Lond). 1989 Aug;77(2):189-94.

A Parallel, Double-blind, Placebo Controlled, Randomized Comparison of an Anti-digoxin Antibody (Digibind) Versus Placebo for the Treatment of Antepartum Patients With Severe Preeclampsia

Details for clinical trial NCT00158743