Clinical trial NCT01158729 - References

Postoperative Hemorrhage — Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates

Citation(s)

•   Agati S, Ciccarello G, Salvo D, Turla G, Undar A, Mignosa C
  Use of a novel anticoagulation strategy during ECMO in a pediatric population: single-center experience. ASAIO J. 2006 Sep-Oct;52(5):513-6.
•   Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Castle V, Powers P
  Development of the human coagulation system in the healthy premature infant. Blood. 1988 Nov;72(5):1651-7.
•   Avidan MS, Levy JH, Scholz J, Delphin E, Rosseel PM, Howie MB, Gratz I, Bush CR, Skubas N, Aldea GS, Licina M, Bonfiglio LJ, Kajdasz DK, Ott E, Despotis GJ
  A phase III, double-blind, placebo-controlled, multicenter study on the efficacy of recombinant human antithrombin in heparin-resistant patients scheduled to undergo cardiac surgery necessitating cardiopulmonary bypass. Anesthesiology. 2005 Feb;102(2):276-84.
•   Avidan MS, Levy JH, van Aken H, Feneck RO, Latimer RD, Ott E, Martin E, Birnbaum DE, Bonfiglio LJ, Kajdasz DK, Despotis GJ
  Recombinant human antithrombin III restores heparin responsiveness and decreases activation of coagulation in heparin-resistant patients during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2005 Jul;130(1):107-13.
•   Bick RL
  Alterations of hemostasis associated with cardiopulmonary bypass: pathophysiology, prevention, diagnosis, and management. Semin Thromb Hemost. 1976 Oct;3(2):59-82. Review.
•   Chambers LA, Cohen DM, Davis JT
  Transfusion patterns in pediatric open heart surgery. Transfusion. 1996 Feb;36(2):150-4.
•   Despotis GJ, Levine V, Joist JH, Joiner-Maier D, Spitznagel E
  Antithrombin III during cardiac surgery: effect on response of activated clotting time to heparin and relationship to markers of hemostatic activation. Anesth Analg. 1997 Sep;85(3):498-506.
•   Engoren MC, Habib RH, Zacharias A, Schwann TA, Riordan CJ, Durham SJ
  Effect of blood transfusion on long-term survival after cardiac operation. Ann Thorac Surg. 2002 Oct;74(4):1180-6.
•   Evans DA, Holder RL, Brawn WJ, Sethia B
  Post-operative blood loss following cardio-pulmonary bypass in children. Eur J Cardiothorac Surg. 1994;8(1):25-9.
•   Hakacova N, Laluhova-Striezencova Z, Zahorec M
  Disturbances of coagulation in neonates with functionally univentricular physiology prior to the first stage of surgical reconstruction. Cardiol Young. 2008 Aug;18(4):397-401. doi: 10.1017/S1047951108002400. Epub 2008 Jun 18.
•   Jaggers J, Lawson JH
  Coagulopathy and inflammation in neonatal heart surgery: mechanisms and strategies. Ann Thorac Surg. 2006 Jun;81(6):S2360-6. Review.
•   Koster A, Chew D, Kuebler W, Habazettl H, Hetzer R, Kuppe H
  High antithrombin III levels attenuate hemostatic activation and leukocyte activation during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2003 Sep;126(3):906-7.
•   Lemmer JH Jr, Despotis GJ
  Antithrombin III concentrate to treat heparin resistance in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2002 Feb;123(2):213-7.
•   Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD
  Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007 Nov 27;116(22):2544-52. Epub 2007 Nov 12.
•   Odegard KC, Zurakowski D, DiNardo JA, Castro RA, McGowan FX Jr, Neufeld EJ, Laussen PC
  Prospective longitudinal study of coagulation profiles in children with hypoplastic left heart syndrome from stage I through Fontan completion. J Thorac Cardiovasc Surg. 2009 Apr;137(4):934-41. doi: 10.1016/j.jtcvs.2008.09.031. Epub 2009 Feb 23.
•   Odegard KC, Zurakowski D, Hornykewycz S, DiNardo JA, Castro RA, Neufeld EJ, Laussen PC
  Evaluation of the coagulation system in children with two-ventricle congenital heart disease. Ann Thorac Surg. 2007 May;83(5):1797-803.
•   Petäjä J, Lundström U, Leijala M, Peltola K, Siimes MA
  Bleeding and use of blood products after heart operations in infants. J Thorac Cardiovasc Surg. 1995 Mar;109(3):524-9.
•   Rinder CS, Rinder HM, Smith MJ, Fitch JC, Tracey JB, Chandler WL, Rollins SA, Smith BR
  Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation. Transfusion. 2006 Jul;46(7):1130-7.
•   Rosenberg RD
  Biochemistry of heparin antithrombin interactions, and the physiologic role of this natural anticoagulant mechanism. Am J Med. 1989 Sep 11;87(3B):2S-9S. Review.
•   Spiess BD, Royston D, Levy JH, Fitch J, Dietrich W, Body S, Murkin J, Nadel A
  Platelet transfusions during coronary artery bypass graft surgery are associated with serious adverse outcomes. Transfusion. 2004 Aug;44(8):1143-8.
•   Villaneuva GB, Danishefsky I
  Evidence for a heparin-induced conformational change on antithrombin III. Biochem Biophys Res Commun. 1977 Jan 24;74(2):803-9.

Antithrombin III Supplementation Prior to Cardiopulmonary Bypass for Neonates

Details for clinical trial NCT01158729