NCT02394457 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Carter BL, Pasupuleti R
Use of intravenous cosyntropin in the treatment of postdural puncture headache. Anesthesiology. 2000 Jan;92(1):272-4.
Collier B
Treatment for PDPH. Br J Anaesth 1994;72:36-7
Foster P
ACTH treatment for post-lumbar puncture headache. Br J Anaesth. 1994 Sep;73(3):429.
Gupta S, Agrawal A
Postdural puncture headache and ACTH. J Clin Anesth. 1997 May;9(3):258.
Sechzer PH, Abel L
Post-spinal anesthesia headache treated with caffeine. Evaluation with demand method. Part I. Curr Therap Res 1978; 24:307-12.
Taivainen T, Pitkänen M, Tuominen M, Rosenberg PH
Efficacy of epidural blood patch for postdural puncture headache. Acta Anaesthesiol Scand. 1993 Oct;37(7):702-5.
VANDAM LD, DRIPPS RD
Long-term follow-up of patients who received 10,098 spinal anesthetics; syndrome of decreased intracranial pressure (headache and ocular and auditory difficulties). J Am Med Assoc. 1956 Jun 16;161(7):586-91.

Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache (PDPH)

Clinical trial NCT02394457 - References